A COMPARISON OF IOPAMIDOL AND METRIZAMIDE FOR CERVICAL MYELOGRAPHY IN THE DOG |
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| Authors: | William R Widmer DVM MS William E Blevins DVM MS Dan Cantwell DVM MS James R Cook Jr DVM Dennis B Denicola DVM PhD |
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| Institution: | Department of Small Animal Clinics, Radiology, School of Veterinary Medicine, Purdue University, West Lafayette, IN 47907;Neurology Sections, School of Veterinary Medicine, Purdue University, West Lafayette, IN 47907;Department of Veterinary Microbiology, Pathology and Public Health, School of Veterinary Medicine, Purdue University, West Lafayette, IN 47907. |
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| Abstract: | Cervical myelography using iopamidol, a new nonionic contrast medium, was studied in nine dogs. Postmyelographic seizure activity, motor evoked potentials, and rectal temperatures were monitored, and myelographic quality was subjectively evaluated. The results were compared with data from eight dogs that had metrizamide myelography. The iopamidol group had fewer seizures ( p < 0.01) but exhibited no difference in motor evoked potential or rectal temperature recordings. Myelographic quality was similar for iopamidol and metrizamide. The study suggests that iopamidol was less neurotoxic than metrizamide for canine cervical myelography. |
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| Keywords: | iopamidol metrizamide canine cervical myelography seizures motor evoked potentials neurotoxicity |
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