| 质粒介导的喹诺酮类耐药基因在鸡源大肠杆菌中的流行 |
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| 引用本文： | 肖方,李新生,张素梅,刘河冰,潘玉善,刘建华,杜向党.质粒介导的喹诺酮类耐药基因在鸡源大肠杆菌中的流行[J].华北农学报,2010,25(1). |
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| 作者姓名： | 肖方 李新生 张素梅 刘河冰 潘玉善 刘建华 杜向党 |
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| 作者单位： | 河南农业大学,牧医工程学院,河南,郑州,450002 |
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| 基金项目： | "十一五"国家科技支撑计划，河南省青年骨干教师资助计划，河南农业大学青年科技创新基金 |
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| 摘 要： | 为了解河南省质粒介导的喹诺酮类耐药基因(qnrA、qnrB、qnrS、qepA和aac(6′)-Ib-cr)在产16S rRNA甲基化酶鸡源大肠杆菌中的流行与分布,分别设计特异性引物对2005-2008年在河南省病鸡病料中分离保存的158株16SrRNA甲基化酶阳性鸡大肠杆菌进行PCR扩增。结果显示,在158株产16S rRNA甲基化酶鸡源大肠杆菌中,qnrA、qnrB、qnrS、qepA和aac(6′)-Ib-cr的检出率分别为0.6%,2.5%,13.9%,2.5%和58.2%。提示质粒介导的喹诺酮类耐药基因在河南省产16S rRNA甲基化酶鸡源大肠杆菌中普遍存在,且以qnrS和aac(6′)-Ib-cr为主。
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| 关 键 词： | 大肠杆菌 喹诺酮类 耐药 质粒介导 |
Prevalence of Plasmid mediated Quinolone Resistance Genes among 16SrRNA Methylase producing Escherichia coli Strains Isolated from Diseased Chickens |
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| XIAO Fang,LI Xin-sheng,ZHANG Su-mei,LIU He-bing,PAN Yu-shan,LIU Jian-hua,DU Xiang-dang.Prevalence of Plasmid mediated Quinolone Resistance Genes among 16SrRNA Methylase producing Escherichia coli Strains Isolated from Diseased Chickens[J].Acta Agriculturae Boreali-Sinica,2010,25(1). |
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| Authors: | XIAO Fang LI Xin-sheng ZHANG Su-mei LIU He-bing PAN Yu-shan LIU Jian-hua DU Xiang-dang |
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| Abstract: | In order to investigate the prevalence of plasmid-mediated quinolone resistance determinants(qnrA,qnrB,qnrS,qepA and aac(6′)-Ib-cr) among 16S rRNA methylase-producing Escherichia coli strains isolated from diseased chickens in Henan province,158 16S rRNA methylase-producing Escherichia coli strains isolated from diseased chickens during the years 2005-2008 were subjected to PCR for the presence of plasmid-mediated quinolone resistance determinants.The results revealed,of 158 16S rRNA methylase-producing E.coli strains,qnrA,qnrB,qnrS,qepA and aac(6′)-Ib-cr were detected in 0.6%,2.5%,13.9%,2.5% and 58.2%,respectively,suggesting plasmid-mediated quinolone resistance determinants were prevalent among 16S rRNA methylase-producing Escherichia coli strains isolated from diseased chickens in Henan province,with qnrS and aac(6′)-Ib-cr dominant. |
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| Keywords: | Escherichia coli Quinolone Resistance Plasmid mediated |
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