| 西红花抗肿瘤作用的研究进展 |
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| 引用本文： | 胡江宁,姚德中,章江生,曹王丽,陈玲芳.西红花抗肿瘤作用的研究进展[J].安徽农业科学,2014(3):699-701,703. |
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| 作者姓名： | 胡江宁 姚德中 章江生 曹王丽 陈玲芳 |
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| 作者单位： | 浙江现代中药与天然药物研究院有限公司,浙江杭州310052;浙江中药制药技术重点实验室,浙江杭州310052;浙江中药制药技术重点实验室,浙江杭州,310052;浙江康恩贝制药股份有限公司,浙江杭州,310052;浙江现代中药与天然药物研究院有限公司,浙江杭州,310052;浙江现代中药与天然药物研究院有限公司,浙江杭州310052;浙江康恩贝药品研究开发有限公司,浙江杭州310052 |
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| 基金项目： | 珍稀贵重中药材西红花的综合开发利用,浙江省中药现代化项目（2013年）. |
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| 摘 要： | 癌症明显影响人类的平均寿命和生活质量,而从蔬菜、草药和香料中提取的天然物质可能有助于预防或治疗多种癌症。西红花具有多种活性成分,具有明显的抗肿瘤潜力,民间中医已将其广泛用于治疗很多疾病。该文通过查阅知网、PubMed和SciFinder中相关文献和资料,获得西红花试验数据,并进行归纳总结,着重介绍了西红花及其主要成分,并对国内外大量的体内、体外试验的研究进展进行综述,发现藏红花具有清除自由基和抗肿瘤活性,并在体外和体内模型中均具有明显的抗肿瘤作用。基于当前数据表明,西红花可被视为有潜力的候选临床抗癌药物。
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| 关 键 词： | 癌症 西红花(Saffron) 化学治疗 活性成分 |
Research Progress of Crocus sativus L. Antitumor Role |
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| Institution: | HU Jiang-ning et al (Zhejiang Modern Chinese Medicine and Natural Drug Research Academy Co. Ltd, Hangzhou, Zheiiang 310052) |
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| Abstract: | Cancer diseases significantly influence human life expectancy and quality. Some natural material, extracted from vegetables, herbs or spices, can prevent or even treat a variety of cancers. Crocus sativus contains some active ingredients, which have been widely used to treat many diseases in folk. The recently studies show that it has significant anti - tumor potential. Crocus sativus and its main ingredients were summarized, and many experiments in vivo or vitro were reviewed to demonstrate its anti-tumor activity. The experimental data of Crocus sativus were found from CNKI, PubMed or SciFinder, and then were summarized. Crocus sativus can clear free radicals and anti - tumor activity in vitro or vivo mod- els. Based on these data, Crocus sativus can be regarded as a potential anti-cancer drug candidate. |
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| Keywords: | Cancer Crocus sativus Chemotherapy Active ingredients |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
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