| 乳牛口服过量维生素A对维生素D3及钙磷代谢的影响 |
| |
| 引用本文： | 金久善,夏兆飞.乳牛口服过量维生素A对维生素D3及钙磷代谢的影响[J].畜牧兽医学报,1994,25(1):25-30. |
| |
| 作者姓名： | 金久善 夏兆飞 |
| |
| 作者单位： | 北京农业大学兽医学院，北京市农场局 |
| |
| 摘 要： | 从北京郊区某农场选取１０头健康成年黑白花乳牛，随机分为试验（５头，每周每头口服维生素Ａ１００万单位）和对照（５头，不作任何处理）两组。８周以后检测发现，试验组血清钙和无机磷水平呈下降趋势；尾椎骨皮质变薄，密度下降，呈现骨质吸收现象；血清碱性磷酸酶显著下降（Ｐ＜０．０５）；其活性代谢产物２５－羟维生素Ｄ３（２５－ＯＨ－Ｄ３）极显著下降（Ｐ＜０．０１）；１，２５－二羟维生素Ｄ３［１，２５－（ＯＨ）２－
|
| 关 键 词： | 乳牛 维生素A 维生素D3 钙磷代谢 |
STUDY ON THE EFFECTS OF ORAL ADMINlSTRATIONOF VITAMIN A ON METABOLISM OF VITAMIN D.CALCIUM AND PHOSPHORUS IN DAIRY COWS |
| |
| Jin Jiushan, Xia Zhaofei, Liang Licheng,Wu Guoli, Fan Guoxiong.STUDY ON THE EFFECTS OF ORAL ADMINlSTRATIONOF VITAMIN A ON METABOLISM OF VITAMIN D.CALCIUM AND PHOSPHORUS IN DAIRY COWS[J].Acta Veterinaria et Zootechnica Sinica,1994,25(1):25-30. |
| |
| Authors: | Jin Jiushan Xia Zhaofei Liang Licheng Wu Guoli Fan Guoxiong |
| |
| Abstract: | Ten healthy and adult dairy cows were selected out from a suburban farm inBeijing and randomly divided into two groups. Each group included five cows. VitaminA (one million I. U. per cow every week) was administered orally in experimental group.After 8 weeks, the results showed that the concentration of serum calcium and inor-ganic phosphorus decreased, but activity of serum alkaline Phosphatase increased mar-kedly (P<0.05), and staining of bone band of its isoenzyme was dark and wide.Thinness of cortex, decrease of density and absorption of substance of bone in tailvertebra were found. The concentration of serum vitamin D, (P<0.05), its active meta-bolites, 25-hydroxycholecalciferol (25-OH-D3) (P<0.01) and 1,25-dihydroxycholeca-lciferol1,25-(OH)2-D3] (no statistical difference) were decreased. So the results showedthat a large amount of vitamin A in body could interfere with normal absorption ofvitamin D3; The results indicated first that excessive vitamin A in dairy cows couldinhibit the hydroxylation of vitamin D, in the liver and kidney, made the productionof its active metabolites decreased and affected furtber on the absorption and metabolismof calcium and phosphorus. As a result the growth and mineralization of the bone wereinfluenced . |
| |
| Keywords: | Dairy cows Vitamin A Vitamin D 25-hydroxycholecalciferol 1 25-dihydroxycholecalciferol Metabolism of calcium and phosphorus |
| 本文献已被 CNKI 维普 等数据库收录！ |
|
