| 恩诺沙星与磺胺间甲氧嘧啶联合药敏试验 |
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| 引用本文： | 郭永刚.恩诺沙星与磺胺间甲氧嘧啶联合药敏试验[J].中国兽药杂志,2009,43(6):9-11. |
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| 作者姓名： | 郭永刚 |
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| 作者单位： | 郑州牧业工程高等专科学校,郑州,450011 |
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| 基金项目： | 河南省教育厅自然科学研究计划项目 |
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| 摘 要： | 为研究氟喹诺酮类药物和磺胺类药物在治疗鸡大肠杆菌病时的相互作用，本试验采用肉汤稀释棋盘法，用恩诺沙星和磺胺间甲氧嘧啶对鸡致病性大肠杆菌进行了体外联合药敏试验。单药恩诺沙星和磺胺间甲氧嘧啶的最小抑菌浓度（MIC）分别为32、256μg／mL；联合用药的MIC分别为8μg／mL和32μg／mL，经计算FIC指数为0．375。结果表明，恩诺沙星与磺胺间甲氧嘧啶联合用药对大肠杆菌呈现协同抗菌作用。
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| 关 键 词： | 恩诺沙星 磺胺间甲氧嘧啶 鸡致病性大肠杆菌 联合药敏试验 |
| 收稿时间： | 1/9/2009 12:00:00 AM |
| 修稿时间： | 2009/2/10 0:00:00 |
Susceptibility Testing of the Combination of Enrofloxacin and Sulfamonomethoxine |
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| guoyonggang.Susceptibility Testing of the Combination of Enrofloxacin and Sulfamonomethoxine[J].Chinese Journal of Veterinary Drug,2009,43(6):9-11. |
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| Authors: | guoyonggang |
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| Institution: | Zhengzhou College of Animal Hubandry Engineering |
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| Abstract: | The study was conducted on the sensitivity of the pathogenic E. coli of chicken to enrofloxacin combined with sulfamonomethoxine. When enrofloxacin and sulfamonomethoxine was used alone, the MIC was 32 μg/mL, 256 μg/mL respectively, when the use of enrofloxacin and sulfamonomethoxine was combined, the MIC was 8 μg/mL,32 μg/mL respectively. The FIC was 0. 375. The result suggested that the combination of enrofloxacin and sulfamonomethoxine demonstrate synergic action on the bacteria. |
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| Keywords: | Enrofloxacin Sulfamonomethoxine Pathogenic E coli of Chicken Combination susceptibility testing |
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