Use of monoclonal antibodies for analyses of Coxiella burnetii major antigens |
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| Authors: | Hotta Akitoyo Zhang Guo Quan Andoh Masako Yamaguchi Tsuyoshi Fukushi Hideto Hirai Katsuya |
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| Institution: | Department of Veterinary Science, National Institute of Infectious Diseases, Tokyo, Japan. |
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| Abstract: | Monoclonal antibodies (MAbs) to major antigens of Coxiella burnetii were produced. Some of the MAbs to a 62-kDa protein antigen, peptidoglycan protein complex and lipopolysaccharide (LPS) O-chains reacted with other bacteria whereas none of the MAbs to outer membrane proteins and LPS outer-core did. The LPS outer-core and OMPs may be useful antigens for specifically detecting antibodies to C. burnetii. |
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