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乳房链球菌对克林霉素耐药基因的定位
引用本文:冯现维,韩文瑜,雷连成,江文正,王世若.乳房链球菌对克林霉素耐药基因的定位[J].中国预防兽医学报,2001,23(2):134-136.
作者姓名:冯现维  韩文瑜  雷连成  江文正  王世若
作者单位:解放军军需大学动物科技系,
摘    要:采用试管稀释法和纸片法测定9株乳房链球菌对克林霉素的耐药性,通过PCR反应检测克林霉素的耐药性基因,并进行测序比较。发现克林霉素对乳房链球菌的抗菌活力较强,克林霉素耐药基因同时存在于乳房链球菌的染色体和质粒上。

关 键 词:乳房链球菌  克林霉素  耐药基因  奶牛
文章编号:1008-0589(2001)02-0134-03
修稿时间:2000年7月30日

Location of the Resistant Gene to Clindamycin in Streptococcus uberis
FENG Xianwei,HAN Wenyu,LEI Liancheng,JIANG Wenzheng,WANG Shiruo.Location of the Resistant Gene to Clindamycin in Streptococcus uberis[J].Chinese Journal of Preventive Veterinary Medicine,2001,23(2):134-136.
Authors:FENG Xianwei  HAN Wenyu  LEI Liancheng  JIANG Wenzheng  WANG Shiruo
Abstract:A total 9 isolates of the Streptococcus uberis were tested for minimal inhibitory concentration (MIC)and antibiotic susceptibility to clindamycin by using test-tube dilution and disc diffusion methods.PCR was used to detect the erm gene in Streptococcus uberis.We find that clindamycin has strong antibacterial activities.Comparision of erm (S.uberis)and ermS(S.sanguis)sequences showed 99%(750/757)conservation,which also suggests erm gene located on both plasmid and chromosome.
Keywords:Streptococcus uberis  Clindamycin  Resistant gene
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