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A comparison of the efficacy of danofloxacin and tylosin in the control of Mycoplasma gallisepticum infection in broiler chicks |
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| Authors: | F T W JORDAN B K HORROCKS S K JONES A C COOPER C J GILES |
| Institution: | Department of Veterinary Pathology, University of Liverpool Veterinary Field Station, Leahurst, Neston, South Wirral, Cheshire;*Department of Pfizer Central Research, Sandwich, Kent, University of Liverpool Veterinary Field Station, Leahurst, Neston, South Wirral, Cheshire;Department of Veterinary Pathology, University of Liverpool Veterinary Field Station, Leahurst, Neston, South Wirral, Cheshire L64 7TE, UK |
| Abstract: | Groups of chicks were infected with a virulent strain of Mycoplasma gallisepticum (MG) and treated with either danofloxacin or tylosin while one infected group was left untreated and a further group was uninfected and untreated. Control of clinical signs and mortality was better with danofloxacin than tylosin and there was significantly (P <0.05)greater weight gain with danofloxacin at 21 days after infection. However ht necropsy the prevalence of lesions of the airsac walls was similar in both groups. MG was recovered from fewer live chicks for the first week following treatment with danofloxacin, but at 2 weeks and at necropsy, at the termination of the experiment, it was recovered from a similar proportion of birds in both treated groups. This was reflected also in the serological results at the end of the trial. |
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