Palliative intravenous cisplatin treatment for concurrent peritoneal and pleural mesothelioma in a dog |
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| Authors: | Seo Kyoung-Won Choi Ul-Soo Jung Yun-Chan Hong Su-Ji Byeun Ye-Eun Kang Min-Soo Pachrin B Kim Wan-Hee Hwang Cheol-Yong Kim Dae-Yong Youn Hwa-Young Lee Chang-Woo |
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| Institution: | Department of Veterinary Internal Medicine, College of Veterinary Medicine, Seoul National University, Korea. |
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| Abstract: | A 10-year-old Maltese dog was presented with abdominal distention and dyspnea. Cytological examination of pleural and peritoneal effusion was suggestive of malignant effusion of glandular origin. Numerous, multifocal, tan to white nodules were disseminated throughout the surface of the abdominal organs and peritoneum at biopsy. Histologically, the tumors were revealed to be an epithelial type of mesothelioma. Neoplastic cells co-expressed cytokeratin and vimentin. Intravenous administration of cisplatin was chosen as the treatment. During treatment, the dog's overall body condition improved and the clinical signs were relieved without significant side effects. The survival time from diagnosis to sudden death by unknown cause was 153 days. |
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