| 硒增强鸡对马立克氏病抵抗力的作用及其机理的研究 |
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| 引用本文： | 黄克和,陈万芳.硒增强鸡对马立克氏病抵抗力的作用及其机理的研究[J].畜牧兽医学报,1996,27(5):448-455. |
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| 作者姓名： | 黄克和 陈万芳 |
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| 作者单位： | 南京农业大学动物医学院 |
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| 摘 要： | １日龄雏鸡２００只，根据１日龄是否用ＨＶＴ冻干苗免疫和基础日粮中是否添加硒的两因子两水平随机均分成４组；在１０日龄各组接种ＭＤ强毒，７０日龄全部扑杀。试验结果表明，各组雏鸡的ＭＤ死亡集中在２１～４４日龄，死亡高峰在３０～３６日龄的一周内，在ＭＤ的发病过程中，动物机体清除氧自由基的能力下降，机体细胞受自由基的攻击程度加重；硒能显著减少ＭＤ的发病率和死亡率；给雏鸡补硒能增强机体清除氧自由基和不饱和过氧化物的能力，减少机体细胞受自由基的攻击程度。作者认为，硒具有增强鸡对ＭＤ抵抗力的作用，硒具有间接和直接清除自由基的能力是增强这种抵抗作用的机理之一。
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| 关 键 词： | 鸡病 马立克氏病 硒 自由基 |
EFFECT OF SELENIUM ON CHICKEN'S RESISTANCE TO MAREK'S DISEASE AND ITS MECHANISM |
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| Huang Kehe,Chen Wanfang.EFFECT OF SELENIUM ON CHICKEN''S RESISTANCE TO MAREK''S DISEASE AND ITS MECHANISM[J].Acta Veterinaria et Zootechnica Sinica,1996,27(5):448-455. |
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| Authors: | Huang Kehe Chen Wanfang |
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| Abstract: | Two hundred 1-day-old healthy chickens were randomly divided into 4 groups.The chickens in group NN were not inoculated with HVT at 1 day of age and given a basal diet not supplemented with selenium. The chickens in group IN were inoculated with HVT at 1 day of age and given a basal diet not supplemented with selenium. The chickens in group NS were not inoculated with HVT at 1 day of age and given a basal diet supplemented with selenium(0.6mg/kg diet).The chickens in group IS were inoculated with HVT at 1 day of age and given a basal diet supplemented with selenium (0.6mg/kg diet).All experimental chickens were inoculated with vMDV at 10 days of age, necropsied and examined for gross and histological lesions at 70 days of age. The experimental results showed that chickens died of MD mainly occurred at 21-44 days of age, High MD mortality concentrated at 30-36 days of age in various groups, the ability of scavenging oxygen free radicals was reduced and the degree of tissue damage caused by oxygen free radicals was aggravated in chickens with MD, selenium could decrease significantly the morbidity and mrtality of MD,and selenium could increase the ability of removing oxygen free radicals and lipid peroxide and alleviate the degree of tissue damage caused by oxygen free radicals.The author thought selenium could increase significantly chicken's resistance to MD, which is related to increasing of the ability in scavenging oxygen free radicals directly and indirectly. |
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| Keywords: | Chickens Marey's disease Selenium Oxygen free radicals |
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