Urine excretion of pentachlorophenol (PCP) in occupational exposure |
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| Authors: | Franco Barbieri Claudio Colosio Helmut Schlitt Marco Maroni |
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| Abstract: | The pharmacokinetics of pentachlorophenol (PCP) excretion in urine was examined in four workers exposed to the biocide in the tannery and wood industries. PCP concentration in urine was significantly higher in morning samples than in afternoon or evening samples. This excretion pattern was observed during an exposure of several shifts and following a four-week holiday period. The estimated half-life for PCP urine excretion was 10 days. Biological monitoring of occupational exposure to PCP should be carried out by measuring the concentration of the compound in urine collected in the morning or before the workshift. |
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| Keywords: | pentachlorophenol pharmacokinetics occupational exposure |
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