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绵羊毛囊及其角蛋白研究进展
引用本文:和东迁,陶金忠,陈丽尧,王俊奎.绵羊毛囊及其角蛋白研究进展[J].中国畜牧兽医,2021,48(1):248-256.
作者姓名:和东迁  陶金忠  陈丽尧  王俊奎
作者单位:宁夏大学农学院, 银川 750021
基金项目:宁夏农业育种专项项目(2013NYYZ0402)
摘    要:毛囊是毛纤维的生长基础,决定毛纤维的性状,角蛋白是毛囊组成的重要成分之一。近年来,对毛囊生长发育和角蛋白基因的挖掘等取得了一定的进展。文章回顾了绵羊角蛋白基因的发现,已经与人类角蛋白基因相当,但在数量和分类上存在差异;笔者介绍了绵羊毛囊的形态学结构,简述了毛囊角蛋白基因的表达定位和影响毛纤维性状的角蛋白,并分析了毛囊中的蛋白质组学技术的应用对毛囊生长发育和毛纤维性状的重要作用,以期为绵羊毛囊生长发育和羊毛性状的分子选育提供新的研究思路。

关 键 词:毛囊  角蛋白  定位  纤维性状  蛋白质组学技术  
收稿时间:2020-06-01

Research Progress of Sheep Hair Follicle and Keratin
HE Dongqian,TAO Jinzhong,CHEN Liyao,WANG Junkui.Research Progress of Sheep Hair Follicle and Keratin[J].China Animal Husbandry & Veterinary Medicine,2021,48(1):248-256.
Authors:HE Dongqian  TAO Jinzhong  CHEN Liyao  WANG Junkui
Institution:School of Agriculture, Ningxia University, Yinchuan 750021, China
Abstract:Hair follicles are the basis for the growth of hair fibers,and determine the properties of wool fibers.Keratin is one of the important components of hair follicles.In recent years,some progresses have been made in hair follicle growth and development and the mining of keratin genes.The article reviewed the discovery of keratin genes,which were already equivalent to human keratin genes,but there were differences in number and classification.This paper introduced the morphological structure of hair follicles,briefly described the gene expression and localization of hair follicles keratin gene and the keratin influencing the character of hair fibers.The important effect of proteomics technology in hair follicle on the growth and development of hair follicle and fiber character was analyzed,in order to provide a new research idea for the growth and development of sheep hair follicles and the molecular breeding of wool traits.
Keywords:hair follicle  keratin  localization  fiber traits  proteomics technology  
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