| LC-MS/MS在硝基呋喃类兽药残留检测中的应用 |
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| 引用本文： | 徐建飞.LC-MS/MS在硝基呋喃类兽药残留检测中的应用[J].中国兽药杂志,2012,46(10):46-49. |
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| 作者姓名： | 徐建飞 |
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| 作者单位： | 上海化工研究院上海稳定同位素工程技术研究中心,上海,200062 |
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| 摘 要： | 综述了目前采用高效液相色谱/串联质谱(LC-MS/MS)法同时测定硝基呋喃类兽药代谢物呋喃唑酮、呋喃它酮、呋喃西林、呋喃妥因残留分析的检测现状、最低检测限以及国内外利用同位素内标法使用LC-MS/MS测定硝基呋喃类兽药残留的检测现状及其达到的最低检测限,并阐明了其应用对我国食品安全体系健康发展的重要意义。
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| 关 键 词： | 兽药残留 高效液相色谱/串联质谱 应用 |
| 收稿时间： | 4/25/2012 9:46:01 PM |
| 修稿时间： | 5/4/2012 12:00:00 AM |
Application of LC-MS/MS in Detection of Nitrofuran Veterinary Drug Residues |
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| XU Jian-fei,WANG Wei,DU Xiao-ning.Application of LC-MS/MS in Detection of Nitrofuran Veterinary Drug Residues[J].Chinese Journal of Veterinary Drug,2012,46(10):46-49. |
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| Authors: | XU Jian-fei WANG Wei DU Xiao-ning |
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| Institution: | Shanghai Research Institute of Chemical Industry |
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| Abstract: | An introduction of the present status regarding veterinary drug residues analysis was made, the paper also made a review of a high performance liquid chromatography - tandem mass spectrometric （ LC - MS/MS） method for simultaneous determination of the nitrofuran metabolites such as furazolidone ,furaltadone ,nitrofurazone and nitrofurantoin, and briefly summarized the limit of detection （LOD） and quantification （LOQ） in veterinary drug residue and isotopic internal standard method using LC -MS/MS, which can reach the lowest limit of detection in veterinary drug residues analysis at home and abroad. The paper elucidated the great importance of the application of stable isotopes in the sane development of China＇ s food safety system. |
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| Keywords: | veterinary drug residues LC-MS/MS application |
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