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Effects of pimozide and LHRH-Aa on carp (Cyprinus carpio L.) oocyte maturation and ovulationin vivo
Authors:K Bieniarz  P Epler  W Popek  R Billard  M Soko?owska
Institution:(1) Department of Ichthyobiology and Fisheries, Academy of Agriculture, Ambrosowa 6, 30-149 Kraków-Mydlniki, Poland;(2) Laboratoire de Physiologie des Poissons, INRA, Jouy-en-Josas, France
Abstract:Effects of pimozide (Pim) and (D-Ala6, Pro9-NEt) LHRH] (LRH-Aa) on common carp oocytes maturation and ovulationin vivo under laboratory and commercial fisheries farm conditions were investigated.Although injections of Pim and LRH-Aa at the doses of 10 mg and 50 µg/kg body weight respectively, did not increase mGtH levels (66.7–155.8 mg/ml) as much as injections of carp pituitary extract (chh) (382.1 ng/ml), induced GtH levels were high enough to induce ovulation. Changes in the ovary caused by Pim and LRH-Aa were similar to those induced by chh, and Pim injected together with LRH-Aa in a single injection gave the same results concerning ovulation induction as when they were applied separately at 6h interval.
Keywords:carp oocytes  maturation  ovulation  pimozide  LRH-Aa
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