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| 几种柏科植物挥发物质及抗肿瘤活性初步研究 | |
| 引用本文： | 蒋继宏,李晓储,高甜惠,何冬宁,陈凤美,张艳平,黄利斌.几种柏科植物挥发物质及抗肿瘤活性初步研究[J].福建林业科技,2006,33(2):52-57. |
| 作者姓名： | 蒋继宏 李晓储 高甜惠 何冬宁 陈凤美 张艳平 黄利斌 |
| 作者单位： | 1. 徐州师范大学江苏省药用植物生物技术重点实验室,江苏,徐州,221000 2. 徐州师范大学江苏省药用植物生物技术重点实验室,江苏,徐州,221000;江苏省林业科学研究院,江苏,南京,211153 3. 江苏省林业科学研究院,江苏,南京,211153 |
| 基金项目： | 国家科技攻关项目;江苏省重点实验室基金 |
| 摘 要： | 用Alamar blue法对提取的5种柏树叶挥发油进行了抗人肺癌细胞实验,结果表明,刺柏、圆柏、龙柏、日本扁柏和绒柏5种树叶挥发油对肺癌细胞NCI-H460抑制率分别为36.93%、78.4%、73.77%、81.22%和56.53%,其中日本扁柏挥发油对肺癌细胞NCI-H460抑制活性最大。采用气-质联用法对6种柏树叶挥发油的化学成分进行了研究,刺柏、圆柏、龙柏、日本扁柏和绒柏5种柏类含有的挥发物质种类分别为32、36、48、22和27种。 |
| 关 键 词： | 柏科植物 抗癌活性 挥发油 树木提取物 |
| 文章编号： | 1002-7351（2006）02-0052-06 |
| 收稿时间： | 2005-11-11 |
| 修稿时间： | 2005-11-112005-12-17 |
Volatile Constituents from the Cupressaceae Plants and Their Antitumor Activities |
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| JIANG Ji-hong,LI Xiao-chu,GAO Tian-hui,HE Dong-ning,CHEN Feng-mei,ZHANG Yan-ping,HUANG Li-bing.Volatile Constituents from the Cupressaceae Plants and Their Antitumor Activities[J].Journal of Fujian Forestry Science and Technology,2006,33(2):52-57. | |
| Authors: | JIANG Ji-hong LI Xiao-chu GAO Tian-hui HE Dong-ning CHEN Feng-mei ZHANG Yan-ping HUANG Li-bing |
| Institution: | 1. Key Laboratory for Biotechnology on Medicinal Plants of Jiangsu Province, Xuzhou Normal University, Xuzhou 221000, China ; 2.Jiangsu Academy of Forestry Nanjin 211153 |
| Abstract: | The antitumor activities of volatile constituents from the Cupressaceae plants against human lung cancer cell line NCI-H460 were determined by alamar blue assay. The results showed that the inhibiting rates of volatile constituents from Juniperus formosana , Sabina chinensis , Sabina chinensis cv. Kaizuca, Chamaecyparis obtuse and Chamaecyparis pisi fera Endt vat. squarros against human lung cancer cell line NCI-H460 were 36.93% ,78.4% ,73.77% ,81.22% and 56.53%, respectively. And the volatile constituents from Chamaecyparis obtuse against the lung cancer line was strongest. These volatile constituents from the five Cupressaceae plants were analyzed by capillary GC-MS method. The kinds of the volatile constituents from Juniperus formosana, Sabina chinensis, Sabina chinensis cv. Kaizuca, Chamaecyparis obtuse and Chamaeeyparis pisifera Endt var. squarros were 32. 36,48.22 and 27, respectively. |
| Keywords: | Cupressaceae plants antitumor activities volatile constituents tree extracts |
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