| 甲基化EGCG的研究现状及展望 |
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| 引用本文： | 伍妍俊,汪小钢,宛晓春.甲基化EGCG的研究现状及展望[J].茶叶科学,2010,30(6):407-413. |
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| 作者姓名： | 伍妍俊 汪小钢 宛晓春 |
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| 作者单位： | 农业部茶及药用植物安全生产重点开放实验室,安徽农业大学,安徽 合肥 230036 |
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| 基金项目： | 现代农业(茶叶)产业技术体系建设专项资金 |
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| 摘 要： | EGCG3"Me于1982年首次从绿茶中被分离出来,并发现它具有潜在的抗过敏活性。近年来,甲基化的EGCG不断从茶叶和体内代谢物中被发现。本文对国内外甲基化EGCG的分离方法、功效和合成方法进行了综述。常见的甲基化EGCG分离方法包括葡聚糖凝胶（Sephadex LH-20）、高速逆流色谱、Toyopearl HW-40S中压柱层析、制备型液相色谱（pHPLC）等方法;甲基化EGCG在抗过敏性、抗细胞毒素、抑制脂肪氧化酶、抑制诱导型一氧化氮合成酶（iNOS）、保护肝细胞等方面都优于EGCG;甲基化EGCG的合成主要包括化学合成和生物合成两种途径。
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| 关 键 词： | 甲基化表没食子儿茶素没食子酸酯 分离 生物学活性 合成 |
| 收稿时间： | 2010-04-26 |
Present Studies and Research Prospects on the Methylated EGCG |
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| WU Yan-jun,WANG Xiao-gang,WAN Xiao-chun.Present Studies and Research Prospects on the Methylated EGCG[J].Journal of Tea Science,2010,30(6):407-413. |
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| Authors: | WU Yan-jun WANG Xiao-gang WAN Xiao-chun |
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| Institution: | Key Laboratory of Tea & Medicinal Plant and Product Safety of Ministry of Agriculture, Anhui Agricultural University, Hefei 230036, China |
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| Abstract: | EGCG3 Me was first isolated from green tea in 1982,and its potential antiallergic activity was reported. In recent years,some other methylated EGCG were discovered in tea or vivo metabolites.The isolation,function and synthesis of methylated EGCG were reviewed in this paper.The separation methods of methylated EGCG including Sephadex LH-20 chromatography,high-speed countercurrent chromatography,Toyopearl HW-40S medium-pressure chromatography,and preparative high performance liquid chromatography(pHPLC) were... |
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| Keywords: | methylated EGCG isolation biological activity synthesis |
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