| 活血消银片对银屑病患者皮损中微血管密度的影响 |
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| 作者姓名： | 钱方 杨志波 |
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| 作者单位： | 深圳市中医院； 湖南省中医院； |
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| 基金项目： | 广东省中医药管理局资助项目(2009039) |
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| 摘 要： | 目的观察活血消银片对血瘀型银屑病患者皮损中微血管密度的影响。方法将40例患者随机分为两组。治疗组20例口服活血消银片,对照组20例口服消银片,疗程8周,观察两组患者治疗前后皮损中微血管密度的改变,并与正常组对照。结果活血消银片与消银片对血瘀型银屑病人皮损中微血管密度改善的程度差异有统计学意义(P﹤0.01),但患者治疗后与正常组比较差异仍有统计学意义(P﹤0.05)。结论活血消银片可明显改善银屑病患者皮损中微血管密度,但仍未完全恢复正常,这可能与银屑病的复发有密切的关系。
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| 关 键 词： | 血瘀型银屑病 活血消银片 微血管密度 临床观察 |
Effects of Huoxue Xiaoyin pills on microvascular density
in patients with psoriasis |
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| Authors: | QIAN Fang YANG Zhi-bo |
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| Institution: | Traditional Chinese Medical Hospital of Shenzhen, Shenzhen, Guangdong 518033, China; Traditional Chinese Medical Hospital of Hunan, Changsha, Hunan 410005, China |
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| Abstract: | To observe the effects of Huoxue Xiaoyin pills on microvascular density
in patients with psoriasis in blood stasis syndrome. Methods40 patients were randomly divided in
to 2 groups, 20patients in reatment group were treated with Huoxue Xiaoyin pills and 20
in control group with Xiaoyin pills in treatment course of 8 weeks, then the chhanges
of microvascular density in lesions of psoriasis were detected by immunohistochemically technique
before and after treatment. ResultsThe changes of the microvascular density in both groups were
significantly different ( <0.01); but it was still different with normal persons ( <0.05). Conclusion
Huoxue Xiaoyin pills is effective obviously to improve microvascular density in patients with psori
asis, but difficult to return to normal, which may be related to that the disease is easy to recure. |
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| Keywords: | psoriasis in blood stasis syndrome Huoxue Xiaoyin pills microvascular density clinical observation |
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