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654—2对山羊内毒素性病理损害的保护效应
引用本文:高洪,高洁.654—2对山羊内毒素性病理损害的保护效应[J].动物医学进展,2000,21(2):51-53.
作者姓名:高洪  高洁
作者单位:[1]云南农业大学动物科技学院,昆明 [2]西南林学院资源学院,昆明
基金项目:云南省应用基础研究基金,国家自然科学基金
摘    要:采用病理学和电镜技术观察了山莨菪碱(654-2)对内毒素(ET)诱导山羊病理损伤的影响。结果表明:ET处理组各组织器官充血、淤血,血管内有中性粒细胞和血小板聚集,并见透明血栓形成,血管内皮细胞肿胀,管壁透明变性、肝、肾等实质器官退行性变化,具有明显的超微结构变化。654-2能有效地缓解或减ET诱导的病理损伤。

关 键 词:山羊  内毒素休克  山莨菪碱  病理损伤  保护效应

Effects of Anisodamine on Endotoxin Induced Pathological Lesions in Goats
GAO Hong ,GAO Jie ,ZHU You shuai ,TANG Zhao xin ,CHEN Wan fang.Effects of Anisodamine on Endotoxin Induced Pathological Lesions in Goats[J].Progress In Veterinary Medicine,2000,21(2):51-53.
Authors:GAO Hong  GAO Jie  ZHU You shuai  TANG Zhao xin  CHEN Wan fang
Institution:GAO Hong 1,GAO Jie 2,ZHU You shuai 1,TANG Zhao xin 3,CHEN Wan fang 3
Abstract:The paper was observed endotoxin induced pathological injuries and anisodamine protection in goats with light microscope and electron microscope.The results showed that viscus blood vessels and micrangiums in the organs were congestion,there were transparent thrombosis,polymorphonuclear leukocyte and platelet acccumulation in blood vessel,injuries of vascular endothelial cell,degenerative changes of liver and kidney.Ultrastructural lesions were also observed in the liver and kidney.Anisodamine effectively alleviated the injuries induced by the endotoxin.
Keywords:goat  endotoxin  anisodamine  pathological  lesions
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