Immune escape of equine herpesvirus 1 and other herpesviruses of veterinary importance |
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Authors: | van der Meulen Karen M Favoreel Herman W Pensaert Maurice B Nauwynck Hans J |
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Institution: | Laboratory of Virology, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, B-9820 Merelbeke, Belgium. karen.vandermeulen@ugent.be |
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Abstract: | Equine herpesvirus (EHV)-1 is a pathogen of horses, well known for its ability to induce abortion and nervous system disorders. Clinical signs may occur despite the presence of a virus-specific immune response in the horse. The current review will summarize the research, on how, EHV-1-infected cells can hide from recognition by the immune system. Research findings on immune evasion of EHV-1 will be compared with those of other herpesviruses of veterinary importance. |
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