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六味中药对养殖场供水渠道真菌的抗菌活性研究
引用本文:蒋国政,李继昌,韩振兴,刘挺,曹宏,王媛.六味中药对养殖场供水渠道真菌的抗菌活性研究[J].中国兽医杂志,2012,48(8):68-70.
作者姓名:蒋国政  李继昌  韩振兴  刘挺  曹宏  王媛
作者单位:1. 东北农业大学动物医学学院,黑龙江哈尔滨,150030
2. 诺伟司国际贸易有限公司,北京海淀,100015
基金项目:黑龙江省留学生归国科学基金,教育部留学回国人员科研启动基金
摘    要:为防止养殖场供水渠道长霉,参照M38-A液体微量稀释法测定六味中药对养殖场供水线分离真菌的抗菌活性。结果显示,所选药物对受试菌均有不同程度的抑制作用,黄连、苦参、蛇床子、黄柏、白鲜皮和土荆皮的MIC几何均值分别为2.2、2.8、9.9、19.8、28.1mg/mL和35.4mg/mL。表明,黄柏、白鲜皮和土荆皮抗菌活性较差,蛇床子有一定的抗菌活性,黄连和苦参具有明显的抑菌、杀菌作用。

关 键 词:抗真菌活性  中药  乙醇提取物

Activity of six traditional Chinese medicine against moulds isolated from waterline of livestock farms
JIANG Guo-zheng , LI Ji-chang , HAN Zhen-xing , LIU Ting , CAO Hong , WANG Yuan.Activity of six traditional Chinese medicine against moulds isolated from waterline of livestock farms[J].Chinese Journal of Veterinary Medicine,2012,48(8):68-70.
Authors:JIANG Guo-zheng  LI Ji-chang  HAN Zhen-xing  LIU Ting  CAO Hong  WANG Yuan
Institution:1.College of Veterinary Medicine,Northeast Agricultural University,Harbin 150030,China 2.Novus International Trade Limited Company,Beijing 100015,China)
Abstract:To prevent mildewing of waterline of livestock farms,the antifungal activity of six Traditional Chinese Medicines(TCMs) against moulds isolated from waterline was measured by M38-A broth microdilution.The six TCMs exhibited different antifungal activity.The geometric mean of MICs of Coptis chinensis Franch,Sophora flavescens Ait.,Cnidium monnieri(L.) Cusson,Phellodendron.chinese Schneid,Dictamnus dasycarpus Turcz.,and Cortex Pseudolaricis were 2.2,2.8,9.9,19.8,28.1 and 35.4 mg/mL,respectively.These results showed that the fungistasis and fungicidal effect of Phellodendron.chinese Schneid,Dictamnus dasycarpus Turcz.,and Cortex Pseudolaricis were poor;Cnidium has some antifungal activity and the other two TCMs showed significant effects against the six moulds.
Keywords:antifungal activity  traditional Chinese medicine  ethanol extracts
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