| 鸡沙门氏菌外膜蛋白亚单位疫苗的研究——Ⅱ油乳剂型(OE)亚单位疫苗的研究 |
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| 引用本文： | 申之义,王凤阳,李利萍,苗儒,关平原,李平安,张七斤,巴开明,郭世宏.鸡沙门氏菌外膜蛋白亚单位疫苗的研究——Ⅱ油乳剂型(OE)亚单位疫苗的研究[J].中国动物检疫,2001,18(3):22-23. |
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| 作者姓名： | 申之义 王凤阳 李利萍 苗儒 关平原 李平安 张七斤 巴开明 郭世宏 |
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| 摘 要： | 用十二烷酰肌氨酸法提取鸡沙门氏菌外膜蛋白，作为抗原，制备油乳剂型（Oil Emulsion OE)亚单位疫苗。该亚单位疫苗为油包水（W/O）型，稳定性良好，安全可靠。对3周龄雏鸡用该疫苗肌注接种，6周龄攻毒，结果表明，接种800ugOMP/只油乳剂型亚单位疫苗的雏鸡对鸡白痢沙门氏菌或鼠伤寒沙门氏菌的攻击具有显著的免疫保护力。
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| 关 键 词： | 鸡 沙门氏菌 外膜蛋白 亚单位疫苗 油乳剂型 免疫保护力 |
Studies on OMP Subunit Vaccine of Chicken Salmonella --II Studies on Oil Emulsion Subunit Vaccine |
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| Shen Zhiyi,Wang Fengyang,Li Liping,Miao Ru,Guan Pingyuan,Li Ping an,Zhang Qijin,Ba Kaiming,Guo Shihong.Studies on OMP Subunit Vaccine of Chicken Salmonella --II Studies on Oil Emulsion Subunit Vaccine[J].China Journal Of Animal Quarantine,2001,18(3):22-23. |
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| Authors: | Shen Zhiyi Wang Fengyang Li Liping Miao Ru Guan Pingyuan Li Ping an Zhang Qijin Ba Kaiming Guo Shihong |
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| Abstract: | The Sarkosyl method was used to extract outer membrane protein (OMP) of chicken Salmonella.The OMP was used to make oil emulsion subunit vaccine.The vaccine was safe for chickens.The chickens immunized with the vaccine could resist the challenge of S.Pullorum and S. Typhimurium. |
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| Keywords: | chicken salmonella outer membrane protain subunit vaccime |
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