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A spontaneous outbreak of colibacillosis in antimicrobial-fed piglets and their response to therapy
Authors:BP Dey  DC Blenden  D Mueller
Institution:

Department of Veterinary Microbiology, College of Veterinary Medicine, University of Missouri, Columbia, MO 65211, U.S.A.

Abstract:In determining the effect of prior feeding of antimicrobials on subsequent antimicrobial therapy in induced colibacillosis of piglets with Escherichia coli serotype O62 (Dey et al., 1977), study groups in one trial developed spontaneous colibacillosis due to a different Escherichia coli serotype O147. This paper reports the results and conclusion drawn from this outbreak.

Both groups, irrespective of antimicrobial feeding, developed disease, and the attack rates for the groups were not significantly different. Neither mortality nor the clinical course of illness in animals without therapy changed significantly as a function of antimicrobial feeding. The antimicrobial feeding had no effect on the therapeutic efficacies of chloramphenicol or chlortetracycline utilized for treating the disease. Chloramphenicol therapy was more effective in terminating the disease.

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