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The toxicity, absorption and excretion of rotenone in oysters (Ostrea edulis), and its degradation in seawater at temperatures near 0°C |
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| Authors: | O B Samuelsen E Solheim H Otter and J P Pedersen |
| Institution: | a Department of Pharmacology and Toxicology, University of Bergen, MFH-bygget, 5021, Bergen, Norway b Institute of Marine Research, Department of Aquaculture, C. Sundts gt. 37, 5000, Bergen, Norway |
| Abstract: | A rapid extraction procedure and a HPLC method for quantitative measurements of the concentration of rotenone in oysters (Ostrea edulis) and in seawater is presented. The absorption rate of rotenone by oysters was rapid. With an average rotenone concentration in the seawater of 26 ppb, the concentration in the oysters reached 4.6 ppm after 4 days of exposure. The t1/2 of the excretion of rotenone was 40 h at 10°C. The absorption rate was highly affected by both the rotenone concentration in the seawater and the seawater temperature. Rotenone was quite stable in seawater at low temperatures. At an average temperature close to 0°C, 18% of the rotenone added was still present 45 days after preparing the solution (1 ppm Gullviks rotenone mixture) in seawater. The acute mortality observed was closely related to the measured concentration of rotenone in the oysters. |
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