| 鹰嘴豆抗性淀粉对高脂饮食小鼠生理功能及肠道菌群影响 |
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| 引用本文： | 毛红艳,徐鑫,于明.鹰嘴豆抗性淀粉对高脂饮食小鼠生理功能及肠道菌群影响[J].新疆农业科学,2021,58(5):929-936. |
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| 作者姓名： | 毛红艳 徐鑫 于明 |
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| 作者单位： | 新疆农业科学院粮食作物研究所,乌鲁木齐 830091 |
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| 基金项目： | 新疆维吾尔自治区区域协同创新专项“中哈杂粮全谷物方便食品开发及示范”(2020E01036);新疆粮油精深加工技术创新平台建设(ZLXM38JG);新疆农业科学院青年基金“鹰嘴豆抗性淀粉对高脂小鼠肠道菌群结构的影响”(xjnkq-2017001) |
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| 摘 要： | 【目的】研究鹰嘴豆抗性淀粉对高脂饮食小鼠生理及肠道菌群的作用,为鹰嘴豆抗性淀粉的应用研究提供依据。【方法】以昆明小鼠为试验动物,用鹰嘴豆抗性淀粉干预,普通饲料、高脂饲料分别对照组和模型组,监测其体重、饮食、排泄等体征变化,检测血清中甘油三酯、总胆固醇、高密度脂蛋白、低密度脂蛋白,统计肝脏指数、腹腔总脂肪系数和肠道菌群数量。【结果】与高脂组相比,鹰嘴豆抗性淀粉+高脂组体重增加量、饮食、排泄显著降低(P<0.05);血清中甘油三酯、总胆固醇、低密度脂蛋白显著降低(P<0.05),高密度脂蛋白显著增加(P<0.05);肝脏指数和腹腔总脂肪系数显著降低(P<0.05);肠道乳酸杆菌和双歧杆菌显著增加(P<0.05),大肠杆菌显著降低(P<0.05)。【结论】鹰嘴豆抗性淀粉对高脂饮食小鼠体重、饮食、排泄具有调节作用,对小鼠血清的血脂成分有缓解作用。
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| 关 键 词： | 鹰嘴豆抗性淀粉 高脂饮食 血脂 肠道菌群 |
| 收稿时间： | 2020-05-29 |
Effects of Chickpea Resistant Starch on Physiology Function and Intestinal Microflora of High-Fat Diet Mice |
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| MAO Hongyan,XU Xin,YU Ming.Effects of Chickpea Resistant Starch on Physiology Function and Intestinal Microflora of High-Fat Diet Mice[J].Xinjiang Agricultural Sciences,2021,58(5):929-936. |
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| Authors: | MAO Hongyan XU Xin YU Ming |
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| Institution: | Research Institute of Food Crops, Xinjiang Academy of Agricultural Sciences, Urumqi 830091, China |
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| Abstract: | 【Objective】 To discuss the influence of chickpea resistant starch on physiology and Intestinal Microflora of high-fat diet mice with a view to providing basis for the usage of chickpea resistant starch. 【Methods】 Based on Kunming mice as experimental animals and the mice fed with the feeds that contain chickpea resistant starch as the therapy groups, common feed group and high fat feed group as the control group and model group. The change of the weight, diet and excretion signs were monitored and the serum triglyceride (TG), total cholesterol (TC), high-density lipoprotein cholesterol (HDL-C), low density lipoprotein (LDL-C) were detected and liver coefficient, total abdominal fat coefficient and intestinal Microflora were calculated. 【Results】 The results showed that compared with the high-fat group, the diet intaking, weight and feces of obese mice were significantly reduced (P<0.05); TG, TC and LDL-C were significantly decreased (P<0.05), and HDL-C was significantly increased (P<0.05); The liver coefficient and total abdominal fat coefficient were significantly reduced (P<0.05); Intestinal lactobacillus and bifidobacterium were significantly increased (P<0.05), and escherichia coli significantly was decreased (P<0.05). 【Conclusion】Chickpea resistant starch can regulate the body weight and diet of mice on high-fat diet, and it also has a positive effect on the excretion of mice. It has a relieving effect on the serum lipid composition of mice, and has an effect on the improvement of the visceral organ coefficient of mice and can regulate the intestinal microflora of mice, which lays a theoretical foundation for the further research and development of functional food of chickpea resistant starch. |
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| Keywords: | chickpea resistant starch high-fat diet blood lipid intestinal microflora |
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