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原场猪大肠杆菌多价灭活苗的制备及免疫效果
引用本文:赵恒章,王丽荣,韩雪飞,董永军,姜金庆,时红攀.原场猪大肠杆菌多价灭活苗的制备及免疫效果[J].贵州农业科学,2006,34(6):74-75.
作者姓名:赵恒章  王丽荣  韩雪飞  董永军  姜金庆  时红攀
作者单位:河南科技学院,动物科学系,新乡,453003
基金项目:河南科技学院大学校科研和教改项目
摘    要:用从豫北一自繁自养大型养猪场发病仔猪分离到的致病性大肠杆菌血清型菌株O101、O64、O138进行培养,经甲醛灭活,以铝胶佐剂,制成原场猪大肠杆菌灭活苗,含菌量为200亿/mL,分别于产前40 d和15 d各注射3~4 mL/头。仔猪出生后,通过哺乳可获得一定量抗大肠杆菌抗体,使仔猪对大肠杆菌病具有一定的抵抗力。试验证明,该灭活苗对同型菌株攻毒保护率达86%以上,对仔猪黄白痢有较好的预防作用。

关 键 词:致病性大肠杆菌  仔猪黄白痢  铝胶苗
文章编号:1001-3601(2006)06-0324-0074-02
收稿时间:2006-02-22
修稿时间:2006-02-222006-04-15

Preparation of Multivalent Inactivated Vaccine of Colon Bacillus (Escherichia coli) and Its Immunity Effect in Pig
ZHAO Heng-zhang,WANG Li-rong,HAN Xue-fei,DONG Yong-jun,JIANG Jin-qing,SHI Hong-pan.Preparation of Multivalent Inactivated Vaccine of Colon Bacillus (Escherichia coli) and Its Immunity Effect in Pig[J].Guizhou Agricultural Sciences,2006,34(6):74-75.
Authors:ZHAO Heng-zhang  WANG Li-rong  HAN Xue-fei  DONG Yong-jun  JIANG Jin-qing  SHI Hong-pan
Institution:Henan Institute of Science and Technology, Xinxiang 453003, China
Abstract:The inactivated vaccine with 20 billion/mL was made from three pathogenic colon bacillus strains isolated from the diseased baby pig of pig farm.The sow was twice injected by 3~4mL of the inactivated vaccine before 40d and 15d of preparation and the baby pig has the certain resistant to colon bacillus by milking.The results show that the preventive rate of the inactivated vaccine to the same strain is above 86%,which is of better preventive effects to yellow scour and white scour of baby pig.
Keywords:pathogenic Escherichia coli  yellow and white scour of piget  inactivated vaccine
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