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成体干细胞的可塑性
引用本文:赵慧英,郑月茂,曹鸿国.成体干细胞的可塑性[J].西北农林科技大学学报(社会科学版),2005,33(1):21-24.
作者姓名:赵慧英  郑月茂  曹鸿国
作者单位:西北农林科技大学,生物工程研究所,陕西,杨凌,712100
基金项目:国家"863"高技术研究发展计划项目(2001AA213081)
摘    要:传统观念认为,成体干细胞只能分化成其自身来源组织的细胞类型。但近年大量的研究表明,成体干细胞可跨系甚至跨胚层分化成在发育上与之无关的其他组织的细胞类型,即具有可塑性。文章对成体干细胞可塑性的研究结果、分化机制、应用前景及需解决的问题等进行了综述。

关 键 词:成体干细胞  可塑性  细胞分化
文章编号:1671-9387(2005)01-0021-04
收稿时间:2003/12/26 0:00:00
修稿时间:2003年12月26

Plasticity of adult stem cells
ZHAO Hui-ying,ZHENG Yue-mao,CAO Hong-guo,WEN Ye-fei,ZHANG Yong.Plasticity of adult stem cells[J].Journal of Northwest Sci-Tech Univ of Agr and,2005,33(1):21-24.
Authors:ZHAO Hui-ying  ZHENG Yue-mao  CAO Hong-guo  WEN Ye-fei  ZHANG Yong
Institution:(Institute of Bio-Technology,Northwest A & F University,Yangling,Shaanxi 712100,China)
Abstract:A long-standing concept has been that organ-specific stem cells are restricted to marking the differentiated cell types of the tissue in which they reside.A recent series of studies,however,show that adult stem cells from one tissue or organ can be induced to trans-differentiate into cells of other organs,system or blastoderm unrelated in development.That is to say,adult stem cells posses plasticity.Here,the paper reviews the current study results and speculates about the underlying mechanisms,clinical application and problem existed in adult stem cells plasticity.
Keywords:adult stem cells  plasticity  cell differentiation
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