Characterization of a pigeon paramyxovirus (PPMV-1) isolated from chickens in South Africa |
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| Authors: | Abolnik C Horner R F Maharaj R Viljoen G J |
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| Institution: | Biotechnology Division, Onderstepoort Veterinary Institute, Private Bag X05, Pretoria, 0110, South Africa. |
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| Abstract: | A paramyxovirus with a thermostability of 60 min (typical of velogenic viruses) and a mean death time of > 90 h (typical of lentogenic viruses) was isolated from layers near Mooi River, South Africa. Our results, based on comparative nucleotide sequence data indicated that the virus is pigeon paramyxovirus 1 (PPMV-1), a variant of Newcastle disease virus. The F0 cleavage site contains a 112RRKKRF117 motif, and the virus had 98% sequence identity with PPMV-1 strains from the Far East. PPMV-1 was last reported in South Africa during the 1980s, with this being the first report of PPMV-1 isolated from chickens in South Africa. |
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