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益肝明目汤治疗糖尿病黄斑水肿的疗效分析
作者姓名:陈向东  覃艮艳  张又玮  孙淑铭  聂辅娇  彭清华
作者单位:湖南中医药大学第一附属医院眼科, 湖南 长沙 410007,湖南中医药大学, 湖南 长沙 410208,湖南中医药大学, 湖南 长沙 410208,湖南中医药大学, 湖南 长沙 410208,湖南中医药大学, 湖南 长沙 410208,湖南中医药大学, 湖南 长沙 410208
基金项目:湖南省自然科学基金资助项目(2015JJ2109);湖南中医药管理局资助项目(201463);湖南省高层次卫生人才“225”工程培养项目资助;国家中医药管理局中医眼科学重点学科;湖南省中医五官科学重点学科;中医诊断学国家重点学科开放基金重点项目(2014-06)。
摘    要:目的 观察益肝明目汤治疗糖尿病黄斑水肿的临床疗效。方法 将49例(91眼)糖尿病黄斑水肿患者随机分为两组,观察组25例49眼,口服益肝明目汤治疗;对照组24例42眼,采用醋酸曲安奈德球后注射治疗,疗程6个月。观察两组患者治疗后视力及黄斑水肿的变化情况,比较两组的综合疗效。结果 治疗6个月后,观察组总有效率93.9%;对照组总有效率76.2%,观察组综合疗效优于对照组,差异有统计学意义(P<0.05)。结论 益肝明目汤治疗糖尿病黄斑水肿远期疗效优于曲安奈德,值得临床推广应用。

关 键 词:糖尿病黄斑水肿  益肝明目汤  曲安奈德  光学相干断层扫描
收稿时间:2016/3/2 0:00:00

Effect of Yigan Mingmu Decoction on Diabetic Macular Edema
Authors:CHEN Xiangdong  QIN Genyan  ZHANG Youwei  SUN Shuming  NIE Fujiao and PENG Qinghua
Institution:Department of Ophalmology, the First Affiliated Hospital of Hunan University of Chinese Medicine, Changsha, Hunan 410007, China,Hunan University of Chinese Medicine, Changsha, Hunan 410208, China,Hunan University of Chinese Medicine, Changsha, Hunan 410208, China,Hunan University of Chinese Medicine, Changsha, Hunan 410208, China,Hunan University of Chinese Medicine, Changsha, Hunan 410208, China and Hunan University of Chinese Medicine, Changsha, Hunan 410208, China
Abstract:Objective To observe the effect of Yigan Mingmu decoction on treatment of diabetic macular edema. Methods 49 cases (91 eyes) of diabetic macular edema patients were randomly divided into two groups. The observation group with 25 cases (49 eyes) was treated with Yigan Mingmu decoction, the control group with 24 cases (42 eyes) was given triamcinolone acetonide retrobulbar injection, the course was for 6 months. The changes of visual acuity and macular edema in the two groups after treatment were observed. Results After treatment of 6 months, the total efficiency of the observation group was 93.88%; the total efficiency of the control group was 76.2%, the effect of observation group was better than the control group, the difference is statistically significant (P<0.05). Conclusion The effect of Yigan Mingmu decoction in treatment of diabetic macular edema is better than that of triamcinolone acetonide.
Keywords:diabetic macular edema  Yigan Mingmu decoction  triamcinolone acetonide  optical coherence tomography
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