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当归四逆汤对糖尿病周围神经病变患者神经传导速度和踝肱指数的影响
作者姓名:陈威妮  刘志龙  段素静  曾利侬
作者单位:珠海市第二人民医院内分泌科, 广东 珠海 519020,珠海市第二人民医院内分泌科, 广东 珠海 519020,珠海市第二人民医院内分泌科, 广东 珠海 519020,珠海市第二人民医院内分泌科, 广东 珠海 519020
基金项目:广东省中医药局课题(20131048)。
摘    要:目的 观察当归四逆汤对糖尿病周围神经病变患者神经传导速度和踝肱指数的影响。方法 将糖尿病周围神经病变患者随机分为对照组30例与治疗组30例,两组均口服甲钴胺作为基础治疗,治疗组加用当归四逆汤治疗,治疗4周后,观察并比较两组患者的总体疗效、周围神经传导速度及踝肱指数的改善情况。结果 治疗组总有效率90.0%显著高于对照组63.3%(P<0.05),且其神经传导速度、踝肱指数改善优于对照组,差异有统计学意义(P<0.05)。结论 当归四逆汤治疗糖尿病周围神经病变有较好的疗效,能增强神经传导速度,改善踝肱指数值,可临床推广应用。

关 键 词:糖尿病周围神经病变  当归四逆汤  神经传导速度  踝肱指数  当归  桂枝  细辛
收稿时间:2016/1/5 0:00:00

Effects of Danggui Sini Decoction on Nerve Conduction Velocity and Ankle-brachial Index of Diabetic Peripheral Neuropathy Patients
Authors:CHEN Weini  LIU Zhilong  DUAN Sujing and ZENG Linong
Institution:Department of Endocrinology, the Second People''s Hospital of Zhuhai, Zhuhai, Guangdong 519020, China,Department of Endocrinology, the Second People''s Hospital of Zhuhai, Zhuhai, Guangdong 519020, China,Department of Endocrinology, the Second People''s Hospital of Zhuhai, Zhuhai, Guangdong 519020, China and Department of Endocrinology, the Second People''s Hospital of Zhuhai, Zhuhai, Guangdong 519020, China
Abstract:Objective To observe the effects of Danggui Sini decoction on nerve conduction velocity and ankle-brachial index (ABI) of diabetic peripheral neuropathy (DPN) patients.Methods The DPN patients were randomly divided into the treatment group and control group,30 cases in each group.Both groups were treated with methycobal pills as the basic treatment,the treatment group was added with Danggui Sini decoction.After 4 weeks treatment,the total curative effects,nerve conduction velocity and ABI were observed.Results The total curative effects of treatment group (90.0%) is better than the control group (63.3%)(P<0.05).The improvements of nerve conduction velocity and ABI in the treatment group were significantly higher than that of control group after treatment (P<0.05).Conclusion Danggui Sini decoction shows good effect in treatment of DPN,which can improve the nerve conduction velocity and ABI.possesses significant clinical effect of totel curative effects,nerve conduction velocity and ABI on DPN patients.It is worthy of the clinical population and application.
Keywords:diabetic peripheral neuropathy  Danggui Sini decoction  nerve conduction velocity  ankle-brachial index  Angelica sinensis  Cassia Twig  asarum
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