Based on the 2×2 table, series of approaches including overall association, interspecific association, percentage co-occurrence (PC) and association coefficient (AC) were used to analyze the interspecific association of Zygophyllum xanthoxylum community in Minqin desert area. The results showed that: overall association was insignificant positive association. Community was in a relatively stable stage. Zygophyllum xanthoxylum as constructive species had obvious advantage. The whole community would developing toward the stable and unrelated direction in Wutuojing, while overall association was insignificant negative association. Community was in a relatively unstable stage in Shiliujing. Only 12% species pairs showed significant correlation in 66 species pairs that consists of 12 mainly species in Wutuojing. The positive association was obvious higher than the negative association. There were high association among most species pairs, especially between Zygophyllum xanthoxylum and the other species pairs, whereas there were no significant correlations by χ2 test. So community was in a relatively stable stage. Only 7.58% species pairs showed significant correlation in 66 species pairs that consisted of 12 mainly species in Shiliujing. The negative association was obvious higher than the positive association. Association coefficient (AC) was 0 between Zygophyllum xanthoxylum and the other species pairs. So community was in a relatively unstable stage. There were positive correlations among community stability, whole association and interspecific association.