| 阿维菌素对雄性鲤鱼血清雌二醇含量的影响 |
| |
| 引用本文： | 马晓燕,胡庚东,杨光,陈家长.阿维菌素对雄性鲤鱼血清雌二醇含量的影响[J].中国农学通报,2010,26(10):365-370. |
| |
| 作者姓名： | 马晓燕 胡庚东 杨光 陈家长 |
| |
| 作者单位： | 1. 中国水产科学研究院淡水渔业研究中心,中国水产科学研究院内陆渔业生态环境和资源重点开放实验室,江苏无锡214081
2. 南京农业大学无锡渔业学院,江苏无锡,214081 |
| |
| 基金项目： | 中央级公益性科研院所基本科研业务费专项资金项目 |
| |
| 摘 要： | 本实验研究了阿维菌素对雄性鲤鱼（Cyprinus carpio）的急性毒性以及在不同暴露浓度和不同作用时间下低剂量阿维菌素对雄性鲤鱼血清雌二醇含量的影响。结果表明：阿维菌素对鲤鱼的24 h、48 h、72h和96 h LC50分别为134.12μg?L-1、60.55μg?L-1、45.31μg?L-1和33.50μg?L-1，安全浓度为3.35μg?L-1；长期（20 d）暴露时，在低浓度（3.2~5.6μg?L-1）范围内阿维菌素对雄性鲤鱼血清雌二醇的合成产生了抑制作用，当浓度为5.6μg?L-1时，抑制作用最强，与对照组相比血清雌二醇含量降低了28.8%；在高浓度组10.0μg?L-1和18.0μg?L-1，鲤鱼血清雌二醇浓度水平与空白对照组相比均没有显著差异（P>0.05）。在5.6μg?L-1浓度下，各处理组时间的血清雌二醇含量均低于对照组，其中第20天时雌二醇含量最低，与对照组相比浓度降低了28.8%（P<0.01）。在染毒鲤鱼血清雌二醇含量和阿维菌素作用时间或暴露浓度之间不存在明显的时间-效应或剂量-效应关系。血液中雌激素含量的变化直接影响到鱼体的生殖功能及性征变化。由此推测，体内因富集阿维菌素所导致血清中雌二醇浓度变化的鱼体可能出现某种程度的生殖缺陷，以致影响到鱼类种族的繁衍1]。
|
| 关 键 词： | 南通、冬小麦、气象、产量、构成因素 南通、冬小麦、气象、产量、构成因素 |
| 收稿时间： | 2009-10-21 |
| 修稿时间： | 2010-01-04 |
Effects of Avermectins on the Serum Estradiol Content in Male Cyprinus carpio. |
| |
| Ma Xiaoyan,Hu Gengdong,Yang Guang,Chen Jiazhang.Effects of Avermectins on the Serum Estradiol Content in Male Cyprinus carpio.[J].Chinese Agricultural Science Bulletin,2010,26(10):365-370. |
| |
| Authors: | Ma Xiaoyan Hu Gengdong Yang Guang Chen Jiazhang |
| |
| Institution: | 1Key Open Laboratory of Ecological Environment and Resources of Inland Fisheries, Freshwater Fisheries Research Center,
Chinese Academy of Fishery Sciences, Wuxi Jiangsu 214081;
2Wuxi Fishery College, Nanjing Agricultural University, Wuxi Jiangsu 214081 |
| |
| Abstract: | Avermectins is considered one of the most commonly used pesticides in China and probably the world. Studies on avermectins acute toxicity toCyprinus carpio and effects of low level avermectins on serum estradiol contents in maleCyprinus carpio at different effecting time and exposure concentrations were done. Results of toxicity test showed that 24 h, 48 h, 72 h and 96 hLC 50 values were 134.12 μg/L, 60.55 μg/L, 45.31 μg/L and 33.50 μg/L respectively. The safety concentration of avermectin toCyprinus carpio was 3.35 μg/L; therefore it was virulent toxic to fish. Under effecting time of 20 days, the synthesis of serum estradiol in male C. carpio was inhibited by avermectin at the lower concentrations ranging from 3.2 to 5.6 μg/L. The strongest inhibiting effect happened when the avermectin concentration was 5.6 μg/L, and the content of serum estradiol reduced by 28.8% compared to the control group. However, the synthesis of serum estradiol had no obvious difference at higher concentrations of 10.0 μg/Land 18.0 μg/L. The contents of serum estradiol in maleC. carpio were lower than the control group at all effecting time at the concentration of 5.6 μg/L, and on the 20thday the serum estradiol content showed the lowest value by induced 28.8% compared to the control one. And there was no significant time-response or dose-response relationship between serum estradiol contents in male C. carpio and the effecting time or exposure concentrations of averectin. It is suggested that low level avermectins could induce depressions of serum estradiol in fish,thus threatening reproduction of fish. |
| |
| Keywords: | serum estradiol zz |
| 本文献已被 维普 万方数据 等数据库收录！ |
| 点击此处可从《中国农学通报》浏览原始摘要信息 |
| 点击此处可从《中国农学通报》下载免费的PDF全文 |
|
