| RNA干扰及其应用进展 |
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| 引用本文： | 孙德惠,才学鹏,常惠芸,独军政.RNA干扰及其应用进展[J].动物医学进展,2006,27(6):1-5. |
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| 作者姓名： | 孙德惠 才学鹏 常惠芸 独军政 |
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| 作者单位： | 1. 中国农业科学院兰州兽医研究所家畜疫病病原生物学国家重点实验室农业部畜禽病毒学重点开放实验室,甘肃兰州730046;甘肃农业大学动物医学院,甘肃兰州730070
2. 中国农业科学院兰州兽医研究所家畜疫病病原生物学国家重点实验室农业部畜禽病毒学重点开放实验室,甘肃兰州730046 |
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| 摘 要： | RNA干扰(RNA interference,RNAi)是一种由双链RNA介导的基因沉默现象。RNAi主要发生在核外,RNAi具有操作简便快速等特点。RNAi现象自发现至今已逾10年,在此期间,已将研究重点由机理研究转向应用研究。文章以RNAi的应用为重点,从RNAi的起源、可能的作用机制、作用特点、研究方法、应用前景及展望等方面进行了综述。
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| 关 键 词： | RNA干扰 双链RNA 基因沉默 |
| 文章编号： | 1007-5038（2006）06-0001-05 |
| 收稿时间： | 2006-03-06 |
| 修稿时间： | 2006年3月6日 |
Progress on Applications of RNA Interference |
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| SUN De-hui,CAI Xue-peng,CHANG Hui-yun,DU Jun-zheng.Progress on Applications of RNA Interference[J].Progress In Veterinary Medicine,2006,27(6):1-5. |
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| Authors: | SUN De-hui CAI Xue-peng CHANG Hui-yun DU Jun-zheng |
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| Institution: | 1. Key Laboratory of Animal Virology of Ministry of Agriculture, State Key Laboratory of Veterinary Etiological Biology, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, Gansu, 730046, China ; 2. College of Veterinary Medicine, Gansu Agricultural University, Lanzhou, Gansu, 730070, China |
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| Abstract: | RNA interference(RNAi) is a phenomenon of gene silence induced by double stranded.RNAi was confirmed mainly acting out of karyon till now.RNAi technique possesses easy and quick characteristics.It was found for over ten years,then shifted focus onto it's application.This paper is mainly related to the application of RNAi in resent years,at the same time,the history,mechanism and character of RNAi as well as the method and advance of RNAi research were reviewed. |
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| Keywords: | RNA interference double stranded RNA gene silence |
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