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Successful use of topical mitomycin C for the treatment of a putative neoplastic vascular mass on the nictitating membrane of a dog
Authors:A Seavers  D Robson  JM Weingarth
Institution:1. Oak Flats Veterinary Clinic, Oak Flats, New South Wales, 2529 Australia;2. Dermatology Department, Melbourne Veterinary Specialist Centre, Glen Waverly, Victoria, 3150 Australia
Abstract:A nine-year-old female desexed Great Dane presented with a painful, proliferative, soft red putative neoplastic vascular mass on the nictitating membrane. Three 7-day cycles of the topical cytotoxic drug mitomycin C 0.04%, applied four times daily to the lesion using a low-dose alternate-week pulse therapy, brought about rapid remission of the lesion. The lesion was still in remission at time of euthanasia some 13 months later.
Keywords:dog  haemangiosarcoma  mitomycin C  ocular  third eyelid
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