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Hexomia饮品对环磷酰胺所致免疫低下小鼠肝、肾功能和抗疲劳能力的影响
引用本文:陈佰慧,曲东,姜成哲,崔明勋.Hexomia饮品对环磷酰胺所致免疫低下小鼠肝、肾功能和抗疲劳能力的影响[J].延边大学农学学报,2011,33(4):273-276.
作者姓名:陈佰慧  曲东  姜成哲  崔明勋
作者单位:延边大学农学院动物医学系,吉林延吉,133000
摘    要:将小鼠分为Hexomia饮品A组、B组和水对照组,试验期间进行小鼠的转棒实验,然后第50天开始连续4d给各组小鼠腹腔注射环磷酰胺,造成免疫低下模型.观察Hexomia饮品的保护作用,第55天时剖检动物,检测小鼠肝肾的SOD,MDA等指标.结果表明,Hexomia饮品A、B可降低免疫低下小鼠肝、肾中MDA含量,有效抑制小鼠肝、肾中自由基的生成.且Hexomia饮品对小鼠抗疲劳起到一定的作用.

关 键 词:Hexomia饮品      小鼠  抗疲劳

Effect of Hexomia on liver, kidney function and anti-fatigue effect in immunosuppression mice induced by cyclophosphamide
CHEN Bai-hui,QU Dong,JIANG Cheng-zhe,CUI Ming-xun.Effect of Hexomia on liver, kidney function and anti-fatigue effect in immunosuppression mice induced by cyclophosphamide[J].Journal of Agricultural Science Yanbian University,2011,33(4):273-276.
Authors:CHEN Bai-hui  QU Dong  JIANG Cheng-zhe  CUI Ming-xun
Institution:(Veterinary Medicine Department,Aricultural College of Yanbian University,Yanji Jilin 133000,China)
Abstract:The mice were randomly divided into three groups, Hexomia mineral water A, Hexomia mineral water B and tap-water group as control. Rotarod test showed that the average stay time of mice on rotarod treadmills were increased on the Hexomia mineral water A and B treatment groups. The weight of each mouse was recorded for each week during about 7 weeks treatment before necropsy. From the 50th day of treatment, cyclophosphamide was intraperitoneally injected for each groups for 4 days. At the end of the experiment, SOD and MDA in the liver and kidney were checked. Eventually Hexomia mineral water has no influence for weight changes of mice in each group. There is obvious significant different in MDA contents in liver and kidney. Hexomia mineral water can protect mouse from immunosuppression induction. Hexomia play a role in anti-fatigue mice.
Keywords:Hexomia mineral water  liver  kidney  mouse  anti-fatigue
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