| 群体感应系统调控细菌生物膜的研究进展 |
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| 引用本文： | 钟华晨,贺银凤.群体感应系统调控细菌生物膜的研究进展[J].畜牧与饲料科学,2020,41(5):7-12. |
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| 作者姓名： | 钟华晨 贺银凤 |
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| 作者单位： | 内蒙古农业大学食品科学与工程学院,内蒙古 呼和浩特010018;内蒙古自治区农牧业科学院资源环境与检测技术研究所,内蒙古 呼和浩特010031;内蒙古农业大学食品科学与工程学院,内蒙古 呼和浩特010018 |
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| 基金项目： | 国家自然科学基金地区科学基金项目（31960467）。 |
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| 摘 要： | 主要介绍了细菌生物膜的概念及其形成过程、细菌群体感应（QS）的概念以及革兰阴性菌的AHL-LuxI/LuxR型QS系统、革兰阳性菌的QS系统、LuxS/AI-2介导的种间QS系统、AI-3/肾上腺素/去甲肾上腺素信息系统4种QS系统的调节机制。就QS系统在细菌中发挥的作用以及对生物膜的调控进行初步阐述，以期为乳酸菌的开发利用和致病菌耐药性的研究提供参考。
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| 关 键 词： | 细菌生物膜 群体感应 乳酸菌 致病菌 |
| 收稿时间： | 2020-04-30 |
Research Advances on Regulative Role of Quorum Sensing System in Formation of Bacterial Biofilm |
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| ZHONG Hua-chen,HE Yin-feng.Research Advances on Regulative Role of Quorum Sensing System in Formation of Bacterial Biofilm[J].Animal Husbandry and Feed Science,2020,41(5):7-12. |
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| Authors: | ZHONG Hua-chen HE Yin-feng |
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| Institution: | 1.College of Food Science and Engineering, Inner Mongolia Agricultural University, Hohhot 010018, China;2.Institute of Resources, Environment and Detection Technology, Inner Mongolia Academy of Agricultural and Animal Husbandry Sciences, Hohhot 010031, China |
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| Abstract: | This paper introduces the bacterial biofilm and its formation process, describes the conception of bacterial quorum sensing （QS） system, and expounds four types of regulative mechanism of QS system, including the AHL-LuxI/LuxR based QS system in Gram-negative bacteria, the QS system in Gram-positive bacteria, the LuxS/AI-2 mediated interspecific QS system, and the AI-3/ epinephrine/norepinephrine signaling system. The roles of QS system in bacteria and its regulative mechanism in formation of bacterial biofilm are elaborated, in hoping to provide references for the development of lactic acid bacteria agents and the investigations on antimicrobial resistance of pathogenic bacteria. |
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| Keywords: | bacterial biofilm quorum sensing lactic acid bacteria pathogenic bacteria |
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