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Fatal Myocardial Degeneration in an Adult Quarter Horse with Vitamin E Deficiency
Authors:Robert Barigye BVM  MSc  PhD  Neil W Dyer DVM  MS  ACVP  Teresa K Newell DVM  PhD  ACVP
Institution:aFrom the Department of Veterinary Diagnostic Services, North Dakota State University;bDepartment of Veterinary & Microbiological Sciences, North Dakota State University
Abstract:A carcass of an adult female Quarter Horse that spontaneously died was received for general investigation at the veterinary diagnostic laboratory of North Dakota State University. Routine necropsy examination demonstrated multiple pale and firm foci in the heart that were histologically consistent with severe myocardial degeneration/necrosis and fibrosis. Analysis of a liver sample confirmed a suboptimal vitamin E level and a selenium value that was within reference range. Because there was no anamnestic indication for ingestion of cardiotoxic plants or evidence of other etiologic factors, vitamin E deficiency was concluded to have led to the development of the myocardial lesions, which precipitated acute heart failure resulting in sudden death.
Keywords:Adult horse  Myocardial degeneration  Vitamin E deficiency
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