| 山药对免疫机能低下小鼠耐缺氧能力的影响 |
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| 引用本文： | 郑素玲.山药对免疫机能低下小鼠耐缺氧能力的影响[J].动物医学进展,2010,31(2):70-73. |
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| 作者姓名： | 郑素玲 |
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| 作者单位： | 唐山师范学院生命科学系,河北唐山,063000 |
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| 摘 要： | 探讨山药对氢化可的松(HC)诱导的免疫机能低下小鼠耐缺氧能力的影响。按析因分析法设计2×2因子,将40只小鼠分为对照组(A),模型组(B),用药组(C),低下用药组(D),B、D组每天腹腔注射HC(20mg/kg),连续21d;自第4天开始,D组注射HC的同时,C、D组每天灌胃山药水煎液(50mg/kg);A、B组灌胃等量蒸馏水;第22天进行常压密闭耐缺氧试验,记录小鼠存活时间,后处死小鼠迅速称其脾脏、胸腺重量,计算脾指数、胸腺指数,常规石蜡切片,HE染色。结果显示,山药可延长免疫机能低下小鼠的缺氧耐受时间,提高脾指数、胸腺指数(P0.05),改善胸腺脾脏的组织结构。山药对HC有一定的颉颃作用。
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| 关 键 词： | 山药 胸腺 脾 耐缺氧 小鼠 |
Effect of Rhizoma dioscorese on the Hypoxia Tolerance in Immunosuppressive Model Mice |
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| ZHENG Su-ling.Effect of Rhizoma dioscorese on the Hypoxia Tolerance in Immunosuppressive Model Mice[J].Progress In Veterinary Medicine,2010,31(2):70-73. |
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| Authors: | ZHENG Su-ling |
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| Institution: | Department of Biology;Tangshan Normal College;Tangshan;Hebei;063000;China |
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| Abstract: | The effect of Rhizoma dioscorese on the hypoxia tolerance in immunosuppressive model mice caused by hydrocortisone was studied.Forty healthy male Kunming mice were randomly divided into 4 groups: group A and C the peritoneal injection(ip.) of physiological saline;group B and D the ip. hydrocortisone(20 mg/kg),for 21 d.The extract of Rhizoma dioscorese were given orally in the mice of C and D groups,and distilled water is given in the mice of A and B groups. On the 22d,the closed anoxia tolerance test was co... |
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| Keywords: | Rhizoma dioscorese thymus spleen hypoxia tolerance mouse |
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