Hydrolysis rate and In vitro anticholinesterase activity of fenitrothion and S-methyl fenitrothion |
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| Authors: | J Kova
i
ov V Btora &#x; Truchlik |
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| Institution: | J. Kova?i?ová,V. Bátora,? Truchlik |
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| Abstract: | Anticholinesterase activity in vitro of pure fenitrothion, S-methyl fenitrothion (SMF) and mixtures of both was studied using different sources of cholinesterase. SMF was two to three orders as active an inhibitor as fenitrothion. In the mixtures, 1 and 5% SMF significantly influenced the I50 value of fenitrothion. The hydrolysis rates of both compounds are given. A method for the synthesis of pure SMF is also described. |
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