| 嗜酸乳杆菌NCFM双精氨酸分泌信号肽蛋白的预测分析 |
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| 引用本文： | 朱德全,王茗悦,姚嘉,张跃华,韩诚武,卢伟,栾积毅,刘向东.嗜酸乳杆菌NCFM双精氨酸分泌信号肽蛋白的预测分析[J].安徽农业科学,2017,45(14). |
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| 作者姓名： | 朱德全 王茗悦 姚嘉 张跃华 韩诚武 卢伟 栾积毅 刘向东 |
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| 作者单位： | 佳木斯大学理学院,黑龙江佳木斯,154007;佳木斯大学生命科学学院,黑龙江佳木斯,154007;佳木斯大学机械工程学院,黑龙江佳木斯,154007 |
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| 基金项目： | 黑龙江省卫生计生委科研项目，佳木斯大学科技创新团队项目 |
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| 摘 要： | 目的]对嗜酸乳杆菌NCFM中Tat途径分泌信号肽蛋白进行预测分析。方法]以嗜酸乳杆菌NCFM基因组序列为对象,采用Signal P4.0、Lipo P1.0、Tat P软件分析该菌株基因组中的双精氨酸途径分泌信号肽蛋白。结果]嗜酸乳杆菌NCFM中有酶切位点也有motif的Tat途径信号肽蛋白94个。结论]对嗜酸乳杆菌NCFM中Tat途径分泌信号肽蛋白的预测分析,为进一步分析该菌胞外蛋白的分泌机制打下基础。
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| 关 键 词： | 嗜酸乳杆菌NCFM 基因组 信号肽蛋白 Tat分泌途径 |
Prediction Analysis of Signal Peptide Proteins of Twin-Arginine Translocation Pathway in Lactobacillus acidophilus NCFM |
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| ZHU De-quan,WANG Ming-yue,YAO Jia,Zhang Yue-hua,Han Cheng-wu,Lu Wei,Luan Ji-yi,LIU Xiang-dong.Prediction Analysis of Signal Peptide Proteins of Twin-Arginine Translocation Pathway in Lactobacillus acidophilus NCFM[J].Journal of Anhui Agricultural Sciences,2017,45(14). |
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| Authors: | ZHU De-quan WANG Ming-yue YAO Jia Zhang Yue-hua Han Cheng-wu Lu Wei Luan Ji-yi LIU Xiang-dong |
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| Abstract: | Objective] To predict their signal peptide proteins secreted by Tat pathway in Lactobacillus acidophilus NCFM.Method] The genome sequences of L.acidophilus NCFM were used to predict to secretory proteins of Tat pathway and functional analysis by using SignalP4.0,LipoP1.0,TatP.Result] There were 94 proteins containing cleavage site of enzyme and motif of Tat pathway in L.acidophilus NCFM.Conclusion] These results lay the foundation for analyzing the secretion mechanism of extracellular protein in L.acidophilus NCFM. |
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| Keywords: | Lactobacillus acidophilus NCFM Genome Signal peptide proteins Tat secretion pathway |
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