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Microdose computed tomographic cardiac angiography in normal cats
Institution:1. Department of Veterinary Clinical Medicine, University of Illinois at Urbana-Champaign, 1008 W. Hazelwood Dr., Urbana, IL 61802, USA;2. Department of Small Animal Medicine and Surgery, University of Georgia, 501 D.W. Brooks Dr., Athens, GA 30602, USA;1. Traunkreis Vet Clinic, Tierklinik Sattledt, Kirchdorferstraße 7, 4642 Sattledt, Austria;2. Swedish University of Agricultural Sciences, Department of Clinical Sciences, P.O. Box 7070, 75007 Uppsala, Sweden;1. Department of Small Animal Clinical Sciences, University of Florida, College of Veterinary Medicine, Gainesville, FL 32608, USA;2. Department of Veterinary Clinical Sciences, Louisiana State University, Baton Rouge, LA 70803, USA;3. Department of Clinical Sciences, Cornell University, College of Veterinary Medicine, Ithaca, NY 14853, USA;1. University of Utah, Comprehensive Arrhythmia Research and Management Center, 30 North 1900 East, Salt Lake City, UT 84132, USA;2. Utah State University, School of Veterinary Medicine, Department of Animal Dairy and Veterinary Sciences, 5600 Old Main Hill, Logan, UT 84322, USA;1. Krishna Institute of Medical Sciences, Hyderabad, India;2. Christian Medical College, Vellore, India;3. Division of Pacing & Electrophysiology, Krishna Institute of Medical Sciences, Hyderabad, India;1. Department of Animal Medicine, Production and Health, University of Padua, Viale dell''Università 16, 35020 Legnaro, PD, Italy;2. Department of Veterinary Medical Sciences, University of Bologna, Via Tolara di Sopra 50, 40064 Ozzano Emilia, BO, Italy
Abstract:ObjectivesTo determine if microdose contrast-enhanced multi-detector computed tomographic angiography (MDCTA) allows characterization of cardiac chambers in lightly sedated normal cats.AnimalsSeven healthy domestic cats.MethodsLightly sedated normal cats were imaged pre-contrast and with microdose (0.22 ml/kg of non-ionic iodinated contrast medium, 300 mg I/ml) triple-phase MDCTA in a motion restriction device.ResultsOn pre-contrast images, the aorta (median: 52.43 Hounsfield units HU], range 27.35–76.74 HU) was outlined by significantly (p = 0.015) lower attenuating periaortic fat (−66.16 HU, −42.62 to −92.77 HU). On post-contrast images, median peak contrast enhancement in the right ventricle (111.77 HU, 36.09–141.60 HU) was achieved in 3.1 s (range 2.9–7.3 s), in the aorta (149.30 HU, 99.43–319.60 HU) and left atrium (180.83 HU, 88.53–266.84 HU) in 6.4 s (range 5.6–7.7 s) and in the left ventricle (147.89 HU, 57.23–245.77 HU) in 7.10 s (range 6.2–11.2 s). Significantly higher attenuation was measured between all chambers and walls, the right ventricular lumen and interventricular septum (median ratio 53.78 HU, range 0.21–83.20 HU), left ventricular lumen and left ventricular free wall (89.32 HU, 38.81–185.95 HU) and aorta and periaortic fat (190.43 HU, 143.22–425.44 HU) on post-contrast images.ConclusionsSufficient biological contrast is available on survey CT to discriminate between the aorta and the left atrium, and microdose MDCTA provides sufficient contrast enhancement for adequate visualization of the heart chambers in normal cats.
Keywords:Feline  Heart  CT  Contrast
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