| 鸭大肠杆菌耐酶抑制剂β-内酰胺酶(IRBLs)的检测及耐药性分析 |
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| 引用本文： | 谷晓霞,刘建华,胡功政,苑丽,潘玉善,王磊,陈玉霞.鸭大肠杆菌耐酶抑制剂β-内酰胺酶(IRBLs)的检测及耐药性分析[J].江西农业大学学报,2010,32(1). |
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| 作者姓名： | 谷晓霞 刘建华 胡功政 苑丽 潘玉善 王磊 陈玉霞 |
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| 作者单位： | 河南农业大学,牧医工程学院,河南,郑州,450002 |
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| 基金项目： | 国家自然科学基金项目(30771624) |
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| 摘 要： | 根据耐酶抑制剂β-内酰胺酶(IRBLs)的耐药表型特点,应用纸片扩散法(K-B法)检测40株鸭大肠杆菌产IRBLs情况并分析产IRBLs菌的耐药性。结果表明:产IRBLs阳性株4株,阳性率为10%,其对阿莫西林、阿莫西林/棒酸、氨苄西林、氨苄西林/舒巴坦、替卡西林/棒酸、氟苯尼考、庆大霉素、新霉素、多西环素耐药,说明IRBLs产生菌已在我国兽医临床上出现,且呈现多重耐药的特点。此外,2株产IRBLs菌对哌拉西林/三唑巴坦敏感,表明三唑巴坦对哌拉西林有一定的保护作用。再者,1株产IRBLs菌对三代头孢耐药,该菌株可能同时产生超广谱β-内酰胺酶(ESBLs)或AmpC酶,这提示IRBLs发展的新趋势。
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| 关 键 词： | 鸭大肠杆菌 耐酶抑制剂β-内酰胺酶 纸片扩散法 耐药性 |
Detection of Inhibitor-resistant β-Lactamase (IRBLs) and Analysis of Drug-resistance of Avian Pathogenic E.coli in Duck |
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| GU Xiao-xia,LIU Jian-hua,HU Gong-zheng,YUAN Li,PAN Yu-shan,WANG Lei,CHEN Yu-xia.Detection of Inhibitor-resistant β-Lactamase (IRBLs) and Analysis of Drug-resistance of Avian Pathogenic E.coli in Duck[J].Acta Agriculturae Universitis Jiangxiensis,2010,32(1). |
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| Authors: | GU Xiao-xia LIU Jian-hua HU Gong-zheng YUAN Li PAN Yu-shan WANG Lei CHEN Yu-xia |
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| Institution: | College of Animal Science and Veterinary Medicine/a>;Henan Agricultural University/a>;Zhengzhou 450002/a>;China |
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| Abstract: | Based on the drug-resistance characters of IRBLs,we studied the prevalence of IRBLs among 40 clinical isolates in duck E.coli was studied by K-B test and the drug-resistance of IRBLs-producer to antibacterial drugs was analyzed.The results showed that 4 isolates produced IRBLs,with resistance to amoxi-cillin,amoxicillin/clavulanic acid,ampicillin,ampicillin/sulbactam,ticarcillin/clavulanicacid,florfenicol,gentamycin,neomycin,sulfadiazine and doxycycline,which suggested that IRBLs-producing isolates had emer... |
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| Keywords: | duck E coli IRBLs K-B test drug-resistance |
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