Dodeca-CLE peptides as suppressors of plant stem cell differentiation |
| |
| Authors: | Ito Yasuko Nakanomyo Ikuko Motose Hiroyasu Iwamoto Kuninori Sawa Shinichiro Dohmae Naoshi Fukuda Hiroo |
| |
| Institution: | Department of Biological Sciences, Graduate School of Science, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan. |
| |
| Abstract: | In plants and animals, small peptide ligands that signal in cell-cell communication have been suggested to be a crucial component of development. A bioassay of single-cell transdifferentation demonstrates that a dodecapeptide with two hydroxyproline residues is the functional product of genes from the CLE family, which includes CLAVATA3 in Arabidopsis. The dodecapeptide suppresses xylem cell development at a concentration of 10(-11) M and promotes cell division. An application, corresponding to all 26 Arabidopsis CLE protein family members, of synthetic dodecapeptides reveals two counteracting signaling pathways involved in stem cell fate. |
| |
| Keywords: | |
| 本文献已被 PubMed 等数据库收录！ |
|
