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伊维菌素耐药及敏感捻转血矛线虫国内分离株的鉴定
引用本文:罗晓平,王鹏龙,李军燕,杨晓野,耿万恒,高娃,白宝霞,赵世华.伊维菌素耐药及敏感捻转血矛线虫国内分离株的鉴定[J].畜牧与饲料科学,2020,41(6):94-99.
作者姓名:罗晓平  王鹏龙  李军燕  杨晓野  耿万恒  高娃  白宝霞  赵世华
作者单位:内蒙古自治区农牧业科学院,内蒙古 呼和浩特 010031;内蒙古农业大学,内蒙古 呼和浩特 010018;内蒙古农业大学,内蒙古 呼和浩特 010018;内蒙古自治区农牧业科学院,内蒙古 呼和浩特 010031;新巴尔虎右旗宝格德乌拉苏木畜牧兽医站,内蒙古 新巴尔虎右旗 021300
基金项目:内蒙古自治区农牧业青年创新基金项目(2017QNJJM05); 国家自然科学基金项目(31660710); 内蒙古自治区农牧业创新基金项目(2020CXJJM06)
摘    要:为解决国内开展驱虫药耐药性相关研究中虫种资源缺乏问题,该研究采用国际通用方法开展了华北地区捻转血矛线虫耐伊维菌素虫株的分离工作,并采用传统形态学方法对其进行鉴定。对来源不同的耐伊维菌素捻转血矛线虫虫株进行分离,结果显示:华北地区分离到了4株对伊维菌素6倍耐药及1株对其敏感的捻转血矛线虫。该研究将为国内开展捻转血矛线虫耐伊维菌素研究及新型驱虫药物的开发提供虫种资源。

关 键 词:捻转血矛线虫  伊维菌素  耐药  分离  鉴定
收稿时间:2020-08-28

Identification of Ivermectin-resistant Strain and Sensitive Strain of Haemonchus contortus in China
LUO Xiao-ping,WANG Peng-long,LI Jun-yan,YANG Xiao-ye,GENG Wan-heng,Gaowa,BAI Bao-xia,ZHAO Shi-hua.Identification of Ivermectin-resistant Strain and Sensitive Strain of Haemonchus contortus in China[J].Animal Husbandry and Feed Science,2020,41(6):94-99.
Authors:LUO Xiao-ping  WANG Peng-long  LI Jun-yan  YANG Xiao-ye  GENG Wan-heng  Gaowa  BAI Bao-xia  ZHAO Shi-hua
Institution:1. Inner Mongolia Academy of Agricultural and Animal Husbandry Sciences,Hohhot 010031,China;2. Inner Mongolia Agricultural University,Hohhot 010018,China;3. Animal Husbandry and Veterinary Medicine Station of Baogedewula Sumu of New Barag Right Banner,New Barag Right Banner 021300,China
Abstract:In order to solve the problem of lacking species resources in the domestic research on the resistance of anthelmintic drugs, this study used international common methods to isolate the ivermectin-resistant strains of Haemonchus contortus in north China, and adopted traditional morphologic method to identify them. Ivermectin-resistant Haemonchus contortus strains from different sources in north China were isolated, and the results showed that 4 strains of Haemonchus contortus were 6 times resistant to ivermectin and 1 strain was susceptible. This research provide species resources for domestic research on ivermectin resistance of Haemonchus contortus and the development of new anthelmintic drugs.
Keywords:Haemonchus contortus  ivermectin  resistance  isolation  identification  
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