Localization of amylin‐like immunoreactivity in the striped velvet gecko pancreas |
| |
| Authors: | H Suzuki T Yamamoto |
| |
| Institution: | 1. Brain Functions and Neuroscience Unit, Department of Oral Science, Graduate School of Dentistry, Kanagawa Dental University, Yokosuka, Japan;2. Department of Biology, University of Teacher Education Fukuoka, Munakata, Fukuoka, Japan |
| |
| Abstract: | Immunohistochemical techniques were employed to investigate the distribution of amylin‐like immunoreactive cells in the pancreas of gecko Homopholis fasciata. Four types of endocrine cells were distinguished: insulin immunoreactive (B cells), pancreatic polypeptide immunoreactive (PP cells), glucagon and pancreatic polypeptide immunoreactive (A/PP cells) and somatostatin immunoreactive cells (D cells). Pancreatic islets contained B, A/PP and D cells, whereas extrainsular regions contained B, D and PP cells. In the pancreatic islets, amylin‐like immunoreactive cells corresponded to B cells, but not to A/PP or D cells. In the extrainsular regions, amylin‐like immunoreactive cells corresponded to either B or PP cells. Amylin secreted from intrainsular B cells may regulate pancreatic hormone secretion in an autocrine and/or a paracrine fashion. On the other hand, amylin secreted from extrainsular PP and B cells, and/or intrainsular B cells may participate in the modulation of calcium homoeostasis in an endocrine fashion. |
| |
| Keywords: | amylin gecko islet islet amyloid polypeptide pancreas reptile |
|
|
