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BALB/c小鼠肺组织中氧化及抗氧化系统的动态研究
引用本文:栾智华,乔健,何桂梅,邓光存,毕建敏,孔富丽,李雪竹,徐强.BALB/c小鼠肺组织中氧化及抗氧化系统的动态研究[J].中国畜牧兽医,2009,36(5):29-31.
作者姓名:栾智华  乔健  何桂梅  邓光存  毕建敏  孔富丽  李雪竹  徐强
作者单位:(1.中国农业大学动物医学院,北京 100193; 2.上海华东师范大学生命科学院,上海 200062)
摘    要:为探讨BALB/c小鼠正常生理状况下肺组织中的氧化及抗氧化系统的动态变化规律,采用分光光度计法分别测定了肺组织中的黄嘌呤氧化酶(xanthine oxidase,XOD)活性、丙二醛(malondialdehyde,MDA)含量、超氧化物歧化酶(superoxide dismutase,SOD)活性变化。结果表明,在第3、6、7、12天BALB/c小鼠肺组织的XOD活性、MDA含量、SOD活性均无显著差异(P>0.05)。说明生理状态下,BALB/c小鼠肺组织中自由基的产生与清除的酶系统之间维持动态平衡。

关 键 词:BALB/c小鼠  丙二醛  黄嘌呤氧化酶  超氧化物歧化酶  

Study on Oxidation and Antioxidation in Lung Tissue of BALB/c Mice
LUAN Zhi-hua,QIAO Jian,HE Gui-mei,DENG Guang-cun,BI Jian-min,KONG Fu-li,LI Xue-zhu,XU Qiang.Study on Oxidation and Antioxidation in Lung Tissue of BALB/c Mice[J].China Animal Husbandry & Veterinary Medicine,2009,36(5):29-31.
Authors:LUAN Zhi-hua  QIAO Jian  HE Gui-mei  DENG Guang-cun  BI Jian-min  KONG Fu-li  LI Xue-zhu  XU Qiang
Institution:(1.College of Veterinary Medicine, China Agricultural University, Beijing 100193, China;2.School of Life Science, East China Normal University, Shanghai 200062, China) P
Abstract:The objective of this study was to explore the changes of oxidative and antioxidative system of the lung tissue in BALB/c mice under normal condition.Malondialdehyde(MDA) concentration,the activity of xanthine oxidase(XOD) and superoxide dismutase(SOD)were measured by spectrophotometer.The results showed that the MDA level,the activity of XOD and SOD in the lung tissue of BALB/c mice did not show any significant difference on day 3,6,7,12(P>0.05).The results indicated that the system of enzyme of generation...
Keywords:BALB/c mice  malondialdehyde  xanthine oxidase  superoxide dismutase  
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