Calcifying aponeurotic fibroma on the paw in a dog |
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| Authors: | Yeseul Yang Du-Min Go Jae-Ha Jung Dansong Seo Sung-Hyun Hwang Dae-Yong Kim Yongbaek Kim |
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| Institution: | Laboratory of Clinical Pathology (Yang, Jung, Seo, Hwang, Yongbaek Kim); BK21 FOUR Program for Future Veterinary Medicine Leading Education and Research Center (Yang, Jung, Seo); Department of Veterinary Pathology (Go, Dae-Yong Kim); Research Institute for Veterinary Science (Dae-Yong Kim, Yongbaek Kim), College of Veterinary Medicine, Seoul National University, Seoul 08826, Korea |
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| Abstract: | A 12-year-old, spayed female, Maltese dog with a round and firm mass on the dorsal part of the left rear paw and a cervical mass was brought to the clinic. The paw mass was contiguous to the adjacent tendon; it was composed of neoplastic mesenchymal cells and had scattered foci of calcification with chondroid differentiation microscopically. The neoplastic cells were positive for vimentin and S100, but negative for desmin and smooth muscle actin. Microscopic features and immunohistochemistry results were consistent with calcifying aponeurotic fibroma (CAF). The cervical mass was composed of polygonal cells forming acini with marked anisocytosis and anisokaryosis and diagnosed as thyroid follicular carcinoma. No recurrence or metastasis occurred during follow-up. To the best of our knowledge, this is the first case of canine CAF with features identical to its human counterparts.Key clinical message:This report describes the rare case of calcifying aponeurotic fibroma on the paw in a dog. This is apparently the first case in the veterinary literature with identical clinical and pathological features to the human counterpart. |
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