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Efficacy of Three Potential Alternatives to Antimicrobial Feed Additives for Weanling Pigs
Institution:1. Hunan International Joint Laboratory of Animal Intestinal Ecology and Health, Animal Nutrition and Human Health Laboratory, School of Life Sciences, Hunan Normal University, Changsha City, Hunan, 410081, China;2. Chinese Academy of Science, Institute of Subtropical Agriculture, Research Center for Healthy Breeding of Livestock and Poultry, Hunan Engineering and Research Center of Animal and Poultry Science and Key Laboratory for Agroecological Processes in Subtropical Region, Scientific Observation and Experimental Station of Animal Nutrition and Feed Science in South-Central, Ministry of Agriculture, Changsha City, Hunan, 410125, China;1. Alltech European Headquarters, Sarney, Summerhill Road, Co. Meath, Dunboyne, Ireland;2. Biosafe – Biological Safety Solutions Ltd, Microkatu 1M, Kuopio, Finland;3. Regulatory Affairs Department, Alltech SARL, Vire, France
Abstract:Three 5-wk growth trials involving 288 weanling pigs were conducted to assess the efficacy of three feed additives as alternatives to antimicrobial feed additives. In Trial 1, a mannanoligosaccha-ride (MOS) source was evaluated with the antimicrobial feed additive carbadox. Treatments included 1) a control diet, 2) a diet containing MOS (0.3% during wk 1 and 0.2% for wk 2 through 5), 3) a diet containing carbadox (55 ppm), and 4) a diet containing both additives. For the 5-wk trial, ADG was 446, 450, 489, and 489 g, and ADFI was 770, 769, 840, and 826 g for Treatments 1 through 4, respectively. No effects of MOS supplementation and no interaction effects of MOS and carbadox were observed (P>0.40). Dietary addition of carbadox resulted in an 8% increase in feed consumption and a 9% improvement in growth rate (P<0.01). In Trial 2, a probiotic consisting of Bacillus licheniformis and subtilis was assessed. Treatments included 1) a control diet, 2) a diet containing Bacillus additive (0.1%), 3) a diet containing carbadox (55 ppm), and 4) a diet containing both additives. Overall ADG was 483, 458, 521, and 503 g, and ADFI was 779, 759, 818, and 795 for Treatments 1 through 4, respectively. Overall there was no Bacillus × carbadox interaction (P>0.40). A slight reduction in growth rate with Bacillus supplementation was observed (P<0.05). Carbadox improved growth rate by 9% and improved feed conversion efficiency by 4% (P<0.01). In Trial 3, increasing dietary levels of a polyaspartate biopolymer product (PAB) (0, 100, 200, and 400 ppm) were assessed. Overall ADG was 502, 491, 491, and 513 g, and ADFI was 889, 836, 823, and 866 for the 0, 100, 200, and 400 ppm PAB treatments, respectively. There was a quadratic change in ADFI with increasing PAB level (P<0.06), but no other effect of PAB was observed. Under the conditions of these trials, no improvements in growth performance with the alternative feed additive products were observed. The antimicrobial feed additive carbadox was effective in improving weanling pig growth performance.
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