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氯氨酮对小白鼠全身麻醉的试验
引用本文:于龙政,张守发.氯氨酮对小白鼠全身麻醉的试验[J].延边大学农学学报,2005,27(4):280-281.
作者姓名:于龙政  张守发
作者单位:延边大学农学院,吉林,龙井,133400
摘    要:为筛选较理想的小白鼠全身麻醉药物,选健康成年小白鼠32只,随机分成4组,用氯氨酮进行全身麻醉,观测麻醉前后小白鼠的呼吸变化及其诱导期、麻醉期和苏醒时间.小白鼠腹腔注射氯氨酮1~1.5mg/10g体重,4~8min可平稳进入麻醉状态,麻醉诱导快,小白鼠无呕吐、躁动等现象,呼吸次数变化不明显,可持续20~40min.氯氨酮用于小白鼠的麻醉,安全有效.

关 键 词:氯氨酮  小白鼠  麻醉
文章编号:1004-7999(2005)04-0280-02
收稿时间:2005-07-25
修稿时间:2005年7月25日

General anesthetic study of ketamine to mice using
YU Long-zheng,ZHANG Shou-fa.General anesthetic study of ketamine to mice using[J].Journal of Agricultural Science Yanbian University,2005,27(4):280-281.
Authors:YU Long-zheng  ZHANG Shou-fa
Institution:Agricultural College of Yanbian University, Longjing Jilin 133400, China
Abstract:To screen better mice general anesthetic drug, thirty-two healthy mice were choosed and divided into four groups stochastically to observe their breathing changes, induction stage, anesthetic stage and revival time. The results showed that the mice used ketamine 1--1.5 mg/10 g under intraperitoneal, could enter into drugged state stably in 4-8 minutes and had no disgorging, restless phenomena, and their respiration rate had no remarkable changes. The anesthetic stage could persist 20 - 40 minutes. Anyway, Ketamin is one kind of safety, comfortable, useable anesthesia drug for general anesthesia of mice.
Keywords:ketamine  mouse  anesthesia
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