A comparison of the cytologic and histologic features of meningiomas in four dogs |
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Authors: | Zimmerman Kurt L Bender Holly S Boon G Daniel Prater M Renee Thorn Catherine E Prater Don Robertson John L Saunders Geoffrey K Sponenberg D Phillip Inzana Karen D Lanz Otto I Wright Eric |
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Institution: | Department of Biomedical Sciences and Pathobiology, Virginia-Maryland Regional College of Veterinary Medicine, Phase II, Duckpond Drive, Blacksburg, VA 24061. |
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Abstract: | Abstract: The cytologic and histologic features of 2 intracranial and 2 spinal (extramedullary cervical) canine meningiomas were compared. Cerebrospinal fluid analysis in 2 cases revealed mild, mixed cell pleocytosis, primarily composed of small lymphocytes and monocytoid cells, with a moderate increase in total protein concentration. Cytologic features suggestive of meningioma included cells with both epithelial and mes-enchymal characteristics and a tendency towards cell clustering. Tumor location also was useful in making a diagnosis. The 4 meningiomas differed histologically from one another, and included angioblastic, psam-momatous, meningotheliomatous, and microcystic anaplastic types, which conformed to a classification scheme for human meningiomas. The classification scheme could not be applied to cytologic specimens. |
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Keywords: | Canine cerebrospinal fluid cytology histopathology meningioma |
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