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Flow cytometric analysis of T cell response in mice infected with Cowdria ruminantium.
Authors:J L Du Plessis  C Gray  M F Van Strijp
Institution:Onderstepoort Veterinary Institute.
Abstract:A 3-fold increase in the numbers of Lyt-2+ T cells in the circulating blood of mice infected and re-infected with the Welgevonden stock of Cowdria ruminantium, as determined by flow cytometry, is supportive evidence that immunity in heartwater is cell-mediated. The rise in Lyt-2+ cells only after re-infection of the mice is further evidence that the development of immunity in heartwater is dependent on the unhindered and adequate replication of C. ruminantium.
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